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NCT03982758
Acute Effect of Isometric Exercise on Blood Pressure in Hypertensive Patients
NA trial testing isometric handgrip exercise in Arterial Hypertension in 80 participants. Status unknown.
18 March 2022
Quick facts
| Lead sponsor | Instituto de Cardiologia do Rio Grande do Sul |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 9 December 2019 |
| Primary completion | 18 March 2022 |
| Estimated completion | 18 March 2022 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- isometric handgrip exercise
- isometric of the lower limbs
Conditions studied
- Arterial Hypertension — all drugs for Arterial Hypertension →
Sponsor
Instituto de Cardiologia do Rio Grande do Sul — full company profile →
Who can join
Adults 40 to 70, any sex, with Arterial Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
International recommendations advocate dynamic or isometric strength training as an adjunct to aerobic exercise. Due to a lack of consensus, this research addresses the acute effects of isometric exercises by handgrip or lower limb isometry as a hypotensive strategy in hypertensive adults.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Post-isometric exercise hypotension occurs irrespective of muscle mass in adults with hypertension: A randomized clinical trial.
Oliveira PC, Dipp T, Waclawovsky G, Lehnen AM. · · 2025 · cited 2× · PMID 40245790 · DOI 10.1016/j.clinsp.2025.100612
Verify or expand the search:
- PubMed search for NCT03982758
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Instituto de Cardiologia do Rio Grande do Sul trials
Trials by the same sponsor.
- NCT06917729 — Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension · NA · not yet recruiting
- NCT06497946 — Effects of SlimTrack® Platform on Diet Adherence, Anthropometry and Arterial Stiffness in Postmenopausal Women · NA · recruiting
- NCT06282302 — Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People · NA · unknown
- NCT06139653 — CardioBreathApp vs IMT in Heart Failure · NA · completed
- NCT03672760 — Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03982758 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto de Cardiologia do Rio Grande do Sul
- Last refreshed: 28 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03982758.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing