NCT03972384 (PIC-UPS) is a NA clinical trial of Post-ICU Problem Solving in Critical Illness, sponsored by Ohio State University.

Who is sponsoring NCT03972384?

NCT03972384 is sponsored by Ohio State University.

What drugs are being tested in NCT03972384?

Interventions in NCT03972384: Post-ICU Problem Solving.

What condition does NCT03972384 study?

NCT03972384 studies Critical Illness, Mechanical Ventilation Complication, Delirium, Cognitive Impairment.

Is NCT03972384 still recruiting?

NCT03972384 is currently completed. Last updated 25 September 2024.

Last reviewed 2024-09-25 · How we verify

NCT03972384: PIC-UPS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults

Completed NA Last updated 25 September 2024

What this trial tests

NA trial testing Post-ICU Problem Solving in Critical Illness in 19 participants. Completed in 1 March 2023.

Timeline

21 January 2022

Primary endpoint
1 March 2023

1 March 2023

Quick facts

Lead sponsor	Ohio State University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	19
Start date	21 January 2022
Primary completion	1 March 2023
Estimated completion	1 March 2023
Sites	1 location across United States

Drugs / interventions tested

Post-ICU Problem Solving

Conditions studied

Critical Illness — all drugs for Critical Illness →
Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
Delirium — all drugs for Delirium →
Cognitive Impairment — all drugs for Cognitive Impairment →

Sponsor

Ohio State University

Who can join

Adults 55 to 89, any sex, with Critical Illness or Mechanical Ventilation Complication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will apply an evidence based program to assist ICU survivors to overcome cognitive problems as a result of their critical illness. This study will determine feasibility of recruitment, retention and engagement with the program as well as acceptability of the program to the participants.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy of Enhanced Rehabilitation Initiated After Hospital Discharge to Improve Quality of Life in Survivors of Critical Care: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Shimizu M, Yoshihiro S, Watanabe S, Aikawa G, et al · · 2024 · PMID 39759637 · DOI 10.7759/cureus.75184

Verify or expand the search:

Other recruiting trials for Critical Illness

Currently open trials in the same condition.

NCT06189924 — Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients · recruiting
NCT07418242 — Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients · recruiting
NCT07101640 — PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysp · Phase 1, PHASE2 · recruiting
NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
NCT07369258 — Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit · NA · recruiting

Other Ohio State University trials

Trials by the same sponsor.

NCT06542458 — Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog · not yet recruiting
NCT07217548 — Solving Stigma Through POV Simulation: Enhancing Pharmacist Empathy-based Practices With Sickle Cell Disease Patients · NA · enrolling by invitation
NCT07215221 — Implementation of TBI-RECOVER in Substance Use Treatment · NA · not yet recruiting
NCT07278427 — Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START · recruiting
NCT07490444 — Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03972384 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ohio State University
Last refreshed: 25 September 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03972384.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing