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NCT03964909
Resting-State Functional MRI in Glioma Patients Before and After Surgery
NA trial testing Functional Magnetic Resonance Imaging in Brain Mass in 29 participants. Completed in 12 November 2024.
12 November 2024
Quick facts
| Lead sponsor | M.D. Anderson Cancer Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 29 |
| Start date | 24 April 2017 |
| Primary completion | 12 November 2024 |
| Estimated completion | 12 November 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Functional Magnetic Resonance Imaging
- Magnetic Resonance Imaging
- Resting State Functional Connectivity Magnetic Resonance Imaging
Conditions studied
- Brain Mass — all drugs for Brain Mass →
- Glioma — all drugs for Glioma →
Sponsor
M.D. Anderson Cancer Center — full company profile →
Who can join
Adults 18 to 75, any sex, with Brain Mass or Glioma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial studies how well resting-state functional magnetic resonance imaging (MRI) and cerebrovascular reactivity (CVR) MRI performed before and after surgery works in measuring the effects on language in patients with glioma. Mapping language function before brain tumor resection is crucial for preventing post-surgical deficits and maximizing restoration of language function following surgery. Additional imaging, such as resting-state functional MRI and CVR MRI, may help measure the language network in the brain before surgery and any effects on language function after surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Safe surgery for glioblastoma: Recent advances and modern challenges.
Gerritsen JKW, Broekman MLD, De Vleeschouwer S, Schucht P, et al · · 2022 · cited 59× · PMID 36127890 · DOI 10.1093/nop/npac019
Verify or expand the search:
- PubMed search for NCT03964909
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03964909 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by M.D. Anderson Cancer Center
- Last refreshed: 15 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03964909.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing