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NCT03962166
Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE
trial in Atrial Fibrillation in 353 participants. Participants enrolled and being followed up; not accepting new ones.
30 December 2023
Quick facts
| Lead sponsor | Helena DOMINGUEZ |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 353 |
| Start date | 7 October 2019 |
| Primary completion | 30 December 2023 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Denmark |
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Left Ventricular Diastolic Dysfunction — all drugs for Left Ventricular Diastolic Dysfunction →
Sponsor
Helena DOMINGUEZ
Who can join
18 and older, any sex, with Atrial Fibrillation or Left Ventricular Diastolic Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Post-operative atrial fibrillation (POAF) is frequently observed after open-heart surgery. Despite numerous attempts to predict POAF, it remains a challenge to correctly identify the patients at risk. New technologies are available but not yet in cooperated in clinical guidelines and prediction models. We aim at identifying patients at risk of AF occurrence/recurrence after open-heart surgery by use of signal processed surface ECG (wavECG). The study is an explorative, prospective cohort study of 100 patients undergoing first-time elective open-heart surgery in the Left Atrial Appendage Closure by Surgery-2 (LAACS-2) trial (NCT03724318). Patients are examined by electrocardiogram (ECG), wavECG, transthoracic echocardiography and continuous heart rhythm monitoring. Primary endpoint is occurrence/recurrence of AF. Left ventricular diastolic dysfunction as evaluated by wavECG will be used to predict incidence of primary endpoint.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Systematic Review of Ongoing Registered Research Studies on Post-Operative Atrial Fibrillation after Cardiac Surgery.
Quan I, Belley-Côté EP, Spence J, Wang A, et al · · 2024 · cited 3× · PMID 39201089 · DOI 10.3390/jcm13164948
Verify or expand the search:
- PubMed search for NCT03962166
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
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- NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other Helena DOMINGUEZ trials
Trials by the same sponsor.
- NCT03724318 — Left Atrial Appendage Closure by Surgery-2 · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03962166 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Helena DOMINGUEZ
- Last refreshed: 16 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03962166.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing