Who is sponsoring NCT03942744?

NCT03942744 is sponsored by Maimónides Biomedical Research Institute of Córdoba.

What drugs are being tested in NCT03942744?

Interventions in NCT03942744: on-line hemodiafiltration.

What condition does NCT03942744 study?

NCT03942744 studies Chronic Kidney Disease Requiring Chronic Dialysis.

Is NCT03942744 still recruiting?

NCT03942744 is currently completed. Last updated 31 March 2022.

Last reviewed 2022-03-31 · How we verify

NCT03942744

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.

Completed NA Last updated 31 March 2022

What this trial tests

NA trial testing on-line hemodiafiltration in Chronic Kidney Disease Requiring Chronic Dialysis in 88 participants. Completed in 25 February 2022.

Timeline

8 November 2018

Primary endpoint
30 November 2021

25 February 2022

Quick facts

Lead sponsor	Maimónides Biomedical Research Institute of Córdoba
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	health services research
Enrollment	88
Start date	8 November 2018
Primary completion	30 November 2021
Estimated completion	25 February 2022
Sites	2 locations across Spain

Drugs / interventions tested

on-line hemodiafiltration

Conditions studied

Chronic Kidney Disease Requiring Chronic Dialysis — all drugs for Chronic Kidney Disease Requiring Chronic Dialysis →

Sponsor

Maimónides Biomedical Research Institute of Córdoba

Who can join

Adults 18 to 80, any sex, with Chronic Kidney Disease Requiring Chronic Dialysis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main aim of this project is to evaluate, in patients with chronic kidney disease (CKD5D), the role of adhesion molecules in leukocyte adhesion and transendothelial migration involved in atherogenesis. This trial is a prospective randomized crossover study in CKD5D hemodialysis patients followed in the Nephrology Unit of the Reina Sofia University Hospital (Cordoba, Spain). The estimated inclusion period is two years, with a follow-up of 24 months. Patients will be randomized to high-flux hemodialysis versus online hemodiafiltration with high convective transport (above 21 liters); after 6 months in each dialysis modality they will be switched the other technique for another 6 months. Then, patients will be maintained during 4 weeks in conventional hemodialysis "wash out period", before being started in the other dialysis modality.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Zhang K, Yang R, Chen J, Qi E, et al · · 2020 · cited 11× · PMID 32478052 · DOI 10.3389/fbioe.2020.00428

Verify or expand the search:

Other recruiting trials for Chronic Kidney Disease Requiring Chronic Dialysis

Currently open trials in the same condition.

NCT07332949 — Impact of Dialysis on Sexuality. · recruiting
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NCT06591702 — Investigation of the Validity, Reliability, and Responsiveness of BETY-BQ in Chronic Kidney Disease, on Dialysis, and Ki · recruiting
NCT06040281 — Smart and Fit for Kidney Transplantation · NA · recruiting

Other Maimónides Biomedical Research Institute of Córdoba trials

Trials by the same sponsor.

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NCT06712485 — Biomarkers in EV Associated With Marrow Adiposity in Anorexia · not yet recruiting
NCT06579846 — 12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03942744 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Maimónides Biomedical Research Institute of Córdoba
Last refreshed: 31 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03942744.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing