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NCT03937284: LiMBaLiP

Lipoprotein Metabolism and Bacterial Lipopolysaccharide in Parkinson's Disease

Completed Last updated 3 May 2019
What this trial tests

trial testing Patients not treated in Parkinson Disease in 45 participants. Completed in 20 October 2017.

Timeline
3 May 2016
Primary endpoint
20 October 2017
20 October 2017

Quick facts

Lead sponsorUniversity of Milan
StatusCompleted
Study typeOBSERVATIONAL
Enrollment45
Start date3 May 2016
Primary completion20 October 2017
Estimated completion20 October 2017
Sites1 location across Italy

Drugs / interventions tested

Conditions studied

Sponsor

University of Milan

Who can join

18 and older, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with Parkinson's disease (PD) present an impaired intestinal permeability with consequent lipopolysaccharide (LPS) translocation in the systemic circulation. Plasmatic lipoproteins play a key role in the detoxification of LPS. The investigators aim to study the relationships between lipoprotein chemical composition and plasma LPS circulation in PD.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Systemic Endotoxemia, Inflammatory Activation, and Lipid Dysregulation in Parkinson's Disease: Evidence from Circulating LPS-Related Biomarkers and Plasma Lipids.
    Della Porta M, Barichella M, Pezzoli G, Cazzola R. · · 2026 · PMID 42123298 · DOI 10.3390/ijms27093711

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Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

Other University of Milan trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03937284.

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