NCT03918603 (ECMO-VILI) is a NA clinical trial of ventral décubitus in ARDS, Human, sponsored by Assistance Publique Hopitaux De Marseille.

Who is sponsoring NCT03918603?

NCT03918603 is sponsored by Assistance Publique Hopitaux De Marseille.

What drugs are being tested in NCT03918603?

Interventions in NCT03918603: ventral décubitus.

What condition does NCT03918603 study?

NCT03918603 studies ARDS, Human.

Is NCT03918603 still recruiting?

NCT03918603 is currently terminated. Last updated 20 July 2023.

Last reviewed 2023-07-20 · How we verify

NCT03918603: ECMO-VILI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Decrease of Lesions Induced by Mechanical Ventilation During ARDS

Terminated NA Last updated 20 July 2023

What this trial tests

NA trial testing ventral décubitus in ARDS, Human in 38 participants. Terminated before completion.

Timeline

3 July 2019

Primary endpoint
23 April 2021

23 June 2021

Quick facts

Lead sponsor	Assistance Publique Hopitaux De Marseille
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	38
Start date	3 July 2019
Primary completion	23 April 2021
Estimated completion	23 June 2021
Sites	1 location across France

Drugs / interventions tested

ventral décubitus

Conditions studied

ARDS, Human — all drugs for ARDS, Human →

Sponsor

Assistance Publique Hopitaux De Marseille — full company profile →

Who can join

Adults 18 to 100, any sex, with ARDS, Human. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Modification of mechanically ventilated lesions by an ultra-protective multimodal strategy compared to a protective strategy in patients with veno-venous ECMO for severe ARDS.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study.
Guervilly C, Fournier T, Chommeloux J, Arnaud L, et al · · 2022 · cited 35× · PMID 36510324 · DOI 10.1186/s13054-022-04272-x
Extracorporeal Gas Exchange for Acute Respiratory Distress Syndrome: Open Questions, Controversies and Future Directions.
Giani M, Giani M, Redaelli S, Siragusa A, et al · · 2021 · cited 10× · PMID 33670987 · DOI 10.3390/membranes11030172
ESICM LIVES 2022: part 1.
· 2022 · cited 4× · PMID 36258101 · DOI 10.1186/s40635-022-00468-1

Verify or expand the search:

Other recruiting trials for ARDS, Human

Currently open trials in the same condition.

NCT07070362 — Digital Early Warning System for Acute Lung Injury in Liver Surgery · recruiting
NCT06572280 — Non-invasive Phrenic Nerve Stimulation in ARDS Patient · NA · recruiting
NCT06119516 — Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study. · NA · recruiting
NCT06321497 — Extracorporeal Carbon Dioxide Removal Using PrismaLung in Reducing Ventilator Induced Lung Injury · recruiting
NCT06486259 — Regional Assessment of the Risk of Lung Injury in Ventilated Patients · recruiting

Other Assistance Publique Hopitaux De Marseille trials

Trials by the same sponsor.

NCT07521644 — Dysbiosis of Methanogenic Archaea and Nanoarchaea in the Oral Microbiome · NA · not yet recruiting
NCT07357025 — Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia · NA · not yet recruiting
NCT07356661 — Evaluation of the Efficacy of Neurofeedback Technique Based on EEG Desynchronization in Epileptic Patients · NA · not yet recruiting
NCT07399327 — Biomarkers of Response to SEEG Thermocoagulation · NA · not yet recruiting
NCT06999499 — Development of an Aid to Melanoma Detection Using Artificial Intelligence Algorithms Based on Images From the VECTRA 3D · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03918603 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assistance Publique Hopitaux De Marseille
Last refreshed: 20 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03918603.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing