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NCT03916900
Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment
NA trial testing Pulpotomy in Pulpitis - Irreversible in 52 participants. Status unknown.
1 June 2020
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 1 June 2019 |
| Primary completion | 1 June 2020 |
| Estimated completion | 1 July 2020 |
Drugs / interventions tested
- Pulpotomy
- Root canal treatment
Conditions studied
- Pulpitis - Irreversible — all drugs for Pulpitis - Irreversible →
Sponsor
Cairo University
Who can join
Adults 9 to 15, any sex, with Pulpitis - Irreversible. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pulpotomy has been proposed in the last decade as a definitive treatment of mature permanent teeth with irreversible pulpitis due to the better understanding of the pulp biology and development of bioactive materials . This technique involves removal of the coronal portion of the pulp that has undergo degenerative and irreversible changes to the level of the canal orifices and leaving the healthy vital radicular portion of the pulp. The surrogate marker for the degree of inflammation and the healing potential of the remaining pulp tissue has been suggested to be the ability to control the bleeding after pulp amputation. By preserving the pulp vitality, this can help in maintaining proprioceptive, reparative, innervation (tooth sensitivity), vascularization, and damping functions. The vital pulp can continue to serve the function of protecting the tooth from overload by means of protective feedback mechanism and preventing fracture because of the presence of pulp and organic tissue in the dentinal tubules..
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vital Pulp Therapy in Teeth with Symptomatic Irreversible Pulpitis: A Systematic Review.
Bafail AS. · · 2024 · cited 1× · PMID 39207274 · DOI 10.3290/j.ohpd.b5718325
Verify or expand the search:
- PubMed search for NCT03916900
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Pulpotomy
Trials testing the same drug.
- NCT04922229 — Comparative Effectiveness in the Management of Irreversible Pulpitis · NA · not yet recruiting
- NCT06293521 — Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries · Phase 2 · recruiting
- NCT07230717 — Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp · NA · not yet recruiting
- NCT07171229 — Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in · NA · not yet recruiting
- NCT06904781 — Treatment Outcomes of Pulpotomy Versus Pulpectomy in Vital Primary Molars Diagnosed With Irreversible Pulpitis · NA · not yet recruiting
Other recruiting trials for Pulpitis - Irreversible
Currently open trials in the same condition.
- NCT07245004 — Effect of Cryotherapy on Postoperative Pain for Pulpotomy · EARLY_PHASE1 · active not recruiting
- NCT07340606 — The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full · NA · recruiting
- NCT07375576 — Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis · NA · recruiting
- NCT07306533 — Effect of Menstrual Phase on the Anesthetic Efficacy · NA · recruiting
- NCT07130214 — The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy · active not recruiting
Other Cairo University trials
Trials by the same sponsor.
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- NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03916900 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 16 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03916900.
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