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NCT03910166
AcoArt VI / Vertebral Artery Ostium Stenosis in China
NA trial testing drug-coated balloon catheter（Orchid, Acotec） in Ischemic Stroke in 180 participants. Completed in 1 October 2023.
7 July 2023
Quick facts
| Lead sponsor | Acotec Scientific Co., Ltd |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 180 |
| Start date | 6 January 2020 |
| Primary completion | 7 July 2023 |
| Estimated completion | 1 October 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- drug-coated balloon catheter（Orchid, Acotec）
- Intracranial artery stent system（APOLLO）
Conditions studied
- Ischemic Stroke — all drugs for Ischemic Stroke →
- Transient Ischemic Attack — all drugs for Transient Ischemic Attack →
Sponsor
Acotec Scientific Co., Ltd
Who can join
Adults 18 to 80, any sex, with Ischemic Stroke or Transient Ischemic Attack. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine whether DEB is not inferior to common bare metal stent using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Paclitaxel Coated Balloon vs. Bare Metal Stent for Endovascular Treatment of Symptomatic Vertebral Artery Origin Stenosis Patients: Protocol for a Randomized Controlled Trial.
Wang Y, Ma Y, Gao P, Chen Y, et al · · 2020 · cited 7× · PMID 33584491 · DOI 10.3389/fneur.2020.579238 -
Effect of drug-coated balloon in patients with severe vertebral artery origin stenosis: A multicenter randomized controlled trial.
Luo J, Jiang C, Wang H, Peng R, et al · · 2026 · cited 1× · PMID 41067866 · DOI 10.1177/17474930251377055
Verify or expand the search:
- PubMed search for NCT03910166
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ischemic Stroke
Currently open trials in the same condition.
- NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
- NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
- NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
- NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
- NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting
Other Acotec Scientific Co., Ltd trials
Trials by the same sponsor.
- NCT05246410 — A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries. · NA · unknown
- NCT04885985 — ACOART BTK RENEW：A Post Market Clinical Study · NA · recruiting
- NCT04899583 — ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon · NA · unknown
- NCT04631055 — AcoArt sICAS: DCB in the Treatment of Symptomatic Intracranial Atherosclerotic Stenosis · NA · completed
- NCT04627870 — ACOART Intracranial ISR Pilot:Intracranial DCB in the Treatment of Intracranial In-stent Restenosis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03910166 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Acotec Scientific Co., Ltd
- Last refreshed: 1 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03910166.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing