Last reviewed · How we verify
NCT04631055
AcoArt sICAS: DCB in the Treatment of Symptomatic Intracranial Atherosclerotic Stenosis
NA trial testing drug coated balloon in Intracranial Atherosclerosis in 180 participants. Completed in 13 April 2023.
10 April 2023
Quick facts
| Lead sponsor | Acotec Scientific Co., Ltd |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 180 |
| Start date | 4 June 2021 |
| Primary completion | 10 April 2023 |
| Estimated completion | 13 April 2023 |
| Sites | 3 locations across China |
Drugs / interventions tested
- drug coated balloon
- stent system
Conditions studied
- Intracranial Atherosclerosis — all drugs for Intracranial Atherosclerosis →
- Stroke — all drugs for Stroke →
Sponsor
Acotec Scientific Co., Ltd
Who can join
Adults 18 to 80, any sex, with Intracranial Atherosclerosis or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the RCT trial is to determine whether DCB is not inferior to stent in treating intracranial stenosis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of drug-coated balloon with bare-metal stent in patients with symptomatic intracranial atherosclerotic stenosis: the AcoArt sICAS randomized clinical trial.
Ma G, Sun D, Jia B, Ling L, et al · · 2026 · cited 1× · PMID 40010849 · DOI 10.1136/jnis-2024-022768
Verify or expand the search:
- PubMed search for NCT04631055
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of drug coated balloon
Trials testing the same drug.
- NCT04119986 — Safety and Efficacy of DCB Therapy for ISR Under the Guidance of QFR (UNIQUE-DCB-II Study ) · NA · not yet recruiting
- NCT04104854 — Safety and Efficacy of DCB Therapy for de Novo Lesions Under the Guidance of QFR in CHD Patients (UNIQUE-DCB-I Study ) · NA · not yet recruiting
Other recruiting trials for Intracranial Atherosclerosis
Currently open trials in the same condition.
- NCT07282041 — Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis · Phase 2, PHASE3 · recruiting
- NCT06902740 — PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis · Phase 4 · recruiting
- NCT05897645 — High-resolution Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaques in Ischemic Stroke · recruiting
- NCT06336174 — Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study · recruiting
- NCT05001984 — Trial of PCSK9 Inhibition in Patients with Acute Stroke and Symptomatic Intracranial Atherosclerosis · Phase 2 · active not recruiting
Other Acotec Scientific Co., Ltd trials
Trials by the same sponsor.
- NCT05246410 — A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries. · NA · unknown
- NCT04885985 — ACOART BTK RENEW：A Post Market Clinical Study · NA · recruiting
- NCT04899583 — ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon · NA · unknown
- NCT04627870 — ACOART Intracranial ISR Pilot:Intracranial DCB in the Treatment of Intracranial In-stent Restenosis · NA · recruiting
- NCT04658901 — ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04631055 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Acotec Scientific Co., Ltd
- Last refreshed: 23 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04631055.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing