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NCT03908658
Inspiratory Muscle Training and Nasal High Flow in Difficult Weaning
NA trial testing Inspiratory muscle Training and Nasal High Flow in High-risk for Reintubation Patients in 146 participants. Status unknown.
1 January 2021
Quick facts
| Lead sponsor | Evangelismos Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 146 |
| Start date | 20 March 2019 |
| Primary completion | 1 January 2021 |
| Estimated completion | 20 March 2021 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Inspiratory muscle Training and Nasal High Flow
- Inspiratory muscle training and Venturi mask
Conditions studied
- High-risk for Reintubation Patients — all drugs for High-risk for Reintubation Patients →
- Weaning Outcome — all drugs for Weaning Outcome →
Sponsor
Evangelismos Hospital
Who can join
Adults 18 to 90, any sex, with High-risk for Reintubation Patients or Weaning Outcome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the present study is to investigate the effectiveness of inspiratory muscle training and nasal high flow oxygen in patients with difficult weaning and high-risk for re-intubation. The hypothesis of the study is that starting inspiratory muscle training once patients are awake and co-operative along with the application of nasal high flow oxygen immediately after extubation will have a beneficial effect in preventive re-intubation in these high-risk patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The combination of inspiratory muscle training and high-flow nasal cannula oxygen therapy for promoting weaning outcomes in difficult-to-wean patients: protocol for a randomised controlled trial.
Patsaki I, Christakou A, Papadopoulos E, Katartzi M, et al · · 2020 · cited 3× · PMID 33015144 · DOI 10.1183/23120541.00088-2020
Verify or expand the search:
- PubMed search for NCT03908658
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03908658 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Evangelismos Hospital
- Last refreshed: 12 February 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03908658.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing