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NCT05464277: INACHOS
Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain Injury
NA trial testing Oxygen in Traumatic Brain Injury in 1 participant. Terminated before completion.
14 July 2024
Quick facts
| Lead sponsor | Evangelismos Hospital |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 1 |
| Start date | 2 December 2022 |
| Primary completion | 14 July 2024 |
| Estimated completion | 14 July 2024 |
| Sites | 2 locations across Greece |
Drugs / interventions tested
- Oxygen — full drug profile →
Conditions studied
- Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
- Acute Respiratory Failure — all drugs for Acute Respiratory Failure →
- Acute Respiratory Distress Syndrome — all drugs for Acute Respiratory Distress Syndrome →
- Acute Brain Injury — all drugs for Acute Brain Injury →
Sponsor
Evangelismos Hospital
Who can join
18 and older, any sex, with Traumatic Brain Injury or Acute Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Despite almost universal usage of supplemental oxygen therapy in patients presenting in the emergency department with traumatic brain injury (TBI), optimal oxygen levels are unclear. The investigators propose a pilot multi-center randomized controlled trial to test the hypothesis that maintaining intermediate normal as opposed to high normal oxygen levels in patients presenting in the emergency department with TBI is feasible, and to obtain preliminary data on the efficacy of the two approaches to oxygen therapy. The aim is that the investigators produce pilot data, which could inform the design of potential subsequent larger clinical trials.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05464277
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Traumatic Brain Injury
Currently open trials in the same condition.
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Other Evangelismos Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05464277 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Evangelismos Hospital
- Last refreshed: 16 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05464277.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing