NCT03894358 is a NA clinical trial of FeFum and 7.5 g prebiotic mixture in Iron Absorption, sponsored by Swiss Federal Institute of Technology.

Who is sponsoring NCT03894358?

NCT03894358 is sponsored by Swiss Federal Institute of Technology.

What drugs are being tested in NCT03894358?

Interventions in NCT03894358: FeFum and 7.5 g prebiotic mixture, FeFum and 3 g prebiotic mixture, Fefum and no prebiotic mixture.

What condition does NCT03894358 study?

NCT03894358 studies Iron Absorption, Gut Microbiota.

Is NCT03894358 still recruiting?

NCT03894358 is currently completed. Last updated 12 May 2020.

Last reviewed 2020-05-12 · How we verify

NCT03894358

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants

Completed NA Last updated 12 May 2020

What this trial tests

NA trial testing FeFum and 7.5 g prebiotic mixture in Iron Absorption in 195 participants. Completed in 4 January 2020.

Timeline

23 July 2019

Primary endpoint
4 January 2020

4 January 2020

Quick facts

Lead sponsor	Swiss Federal Institute of Technology
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	195
Start date	23 July 2019
Primary completion	4 January 2020
Estimated completion	4 January 2020
Sites	1 location across Kenya

Drugs / interventions tested

FeFum and 7.5 g prebiotic mixture
FeFum and 3 g prebiotic mixture
Fefum and no prebiotic mixture

Conditions studied

Iron Absorption — all drugs for Iron Absorption →
Gut Microbiota — all drugs for Gut Microbiota →

Sponsor

Swiss Federal Institute of Technology

Who can join

Adults 6 Months to 11 Months, any sex, with Iron Absorption or Gut Microbiota. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to measure the effect of a prebiotic (high dose/low dose) mixture at different doses within a wheat-based instant cereal, on fractional iron absorption (FIA), gut microbiota and inflammation after three weeks. FIA will be compared with and without three weeks of pre-feeding with two different doses of the prebiotic mixture.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Gut microbiome function and composition in infants from rural Kenya and association with human milk oligosaccharides.
Derrien M, Mikulic N, Uyoga MA, Chenoll E, et al · · 2023 · cited 27× · PMID 36794816 · DOI 10.1080/19490976.2023.2178793
Prebiotics increase iron absorption and reduce the adverse effects of iron on the gut microbiome and inflammation: a randomized controlled trial using iron stable isotopes in Kenyan infants.
Mikulic N, Uyoga MA, Stoffel NU, Derrien M, et al · · 2024 · cited 17× · PMID 38042412 · DOI 10.1016/j.ajcnut.2023.11.018

Verify or expand the search:

Other recruiting trials for Iron Absorption

Currently open trials in the same condition.

NCT07139821 — Dietary Iron Requirements · recruiting
NCT07315295 — Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya · NA · recruiting
NCT07517562 — The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Ener · NA · active not recruiting
NCT06327529 — Zinc and Iron Absorption From Common Beans in Young Adult Women · NA · recruiting
NCT05973552 — Iron Absorption and Requirements in Pregnancy and Lactation · recruiting

Other Swiss Federal Institute of Technology trials

Trials by the same sponsor.

NCT07182734 — Feasibility of Unsupervised Therapy After Neurological or Orthopaedical Injury in the Home Setting With a Hand Rehabilit · NA · not yet recruiting
NCT06725784 — Feasibility and Cost of Robot-assisted Upper Limb Rehabilitation with Different Levels of Supervision · NA · recruiting
NCT06851130 — Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women · NA · recruiting
NCT06149975 — Feasibility of a Motor-cognitive Training Program in Patients With Traumatic Brain Injury · NA · completed
NCT06116669 — Effects of Oral Iron Supplementation Before vs at Time of Vaccination on Immune Response in Iron Deficient Kenyan Women · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03894358 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Swiss Federal Institute of Technology
Last refreshed: 12 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03894358.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing