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NCT07315295: SAMI
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
NA trial testing Iron absorption from RUTF on Day 0 in Iron Absorption in 68 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | ETH Zurich |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 68 |
| Start date | 23 December 2025 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 June 2026 |
| Sites | 2 locations across Kenya, Switzerland |
Drugs / interventions tested
- Iron absorption from RUTF on Day 0
- Treatment with RUTF for 80 days
- Iron absorption from RUTF on Day 20
- Iron absorption from RUTF on Day 40
- Iron absorption from RUTF on Day 60
Conditions studied
- Iron Absorption — all drugs for Iron Absorption →
- Iron Deficiencies — all drugs for Iron Deficiencies →
- Severly Acutely Malnourished Children — all drugs for Severly Acutely Malnourished Children →
- Malnutrition in Children — all drugs for Malnutrition in Children →
Sponsor
ETH Zurich — full company profile →
Who can join
Adults 12 Months to 54 Months, any sex, with Iron Absorption or Iron Deficiencies. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia. The current RUTF formulation may have an excessively high iron content. In severely acutely malnourished (SAM) children, iron cannot be properly absorbed, leading to life-threatening diarrhea. The overall aim of this project is to develop an improved RUTF treatment that addresses acute malnutrition and anemia in children, ensuring both safety and efficacy. Specifically, to assess the impact of malnutrition on fractional iron absorption (FIA) from RUTFs in children, by comparing healthy children to those with acute malnutrition and by tracking changes in FIA in malnourished children over the course of treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07315295
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Related trials
Other recruiting trials for Iron Absorption
Currently open trials in the same condition.
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- NCT06327529 — Zinc and Iron Absorption From Common Beans in Young Adult Women · NA · recruiting
- NCT05973552 — Iron Absorption and Requirements in Pregnancy and Lactation · recruiting
Other ETH Zurich trials
Trials by the same sponsor.
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- NCT06856291 — Response to Semaglutide in Non-diabetic Obese Patients With Varying Degrees of Insulin Resistance · recruiting
- NCT06814327 — Assessment of Organ Failure Risk Predictions in ICU · active not recruiting
- NCT06138990 — Pharmacoscopy-guided Clinical Standard-of-care in r/r AML · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07315295 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by ETH Zurich
- Last refreshed: 2 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07315295.
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