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NCT03890406

The Effect of Deep Neuromuscular Blockade on Requirement of Intravenous Anesthetic Agent

Completed NA Last updated 30 June 2020
What this trial tests

NA trial testing Rocuronium: PTC(Post-tetanic count) 1~2 in Laparoscopy in 88 participants. Completed in 31 March 2020.

Timeline
1 April 2019
Primary endpoint
31 December 2019
31 March 2020

Quick facts

Lead sponsorSeoul National University Bundang Hospital
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment88
Start date1 April 2019
Primary completion31 December 2019
Estimated completion31 March 2020
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Seoul National University Bundang Hospital

Who can join

18 and older, any sex, with Laparoscopy or General Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Recently, deep neuromuscular blockade during general anesthesia has been studied by many authors regarding various effects upon patients' outcomes and surgical conditions. We believe deep neuromuscular blockade can be especially beneficial in laparoscopic surgery, because it can expand surgical space and prevent patients' minute movements that can disturb precise operations. In clinical situations, anesthetists tend to compensate the insufficiency of neuromuscular blockade by increasing the dose of other anesthetic agents, which can prolong patients' recovery time and impair the surgical condition. In this study, we plan to divide the patients into 2 groups according to the depth of neuromuscular blockade, and compare the dose of anesthetic agent used to maintain surgical condition.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Effects of depth of neuromuscular blockade on the BIS-guided propofol requirement: A randomized controlled trial.
    Nam SW, Oh AY, Koo BW, Kim BY, et al · · 2021 · cited 2× · PMID 34398011 · DOI 10.1097/md.0000000000026576

Verify or expand the search:

Other recruiting trials for Laparoscopy

Currently open trials in the same condition.

Other Seoul National University Bundang Hospital trials

Trials by the same sponsor.

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Data sources for this page

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