NCT03888196: GinsengRun

Evaluation of the Efficacy of Panax Ginseng on Lipid Metabolism in Men and the Relationship With Sports Practice.

Completed EARLY_PHASE1 Last updated 2 May 2019

What this trial tests

EARLY_PHASE1 trial testing Panax Ginseng Supplementation in Sports Physical Therapy in 40 participants. Completed in 15 January 2019.

Timeline

1 September 2016

Primary endpoint
1 November 2018

15 January 2019

Quick facts

Lead sponsor	Universitat de Lleida
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	40
Start date	1 September 2016
Primary completion	1 November 2018
Estimated completion	15 January 2019

Drugs / interventions tested

• Panax Ginseng Supplementation
• Placebo Supplementation

Conditions studied

• Sports Physical Therapy — all drugs for Sports Physical Therapy →

Sponsor

Universitat de Lleida

Who can join

18 and older, male only, with Sports Physical Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Panax Ginseng (P ginseng), C.A. Meyer, Red, Chinese or Korean ginseng is a plant from eastern Asia and is one of the most widely used herbal products in the world. P ginseng has been been used for many years for different medical therapies. Previous studies have demonstrate that P. ginseng root extract supplementation may promote fat oxidation, increase hepatic glycogen levels and produce a glycogen-sparing and antifatigue effect during exercise in swimming rats. Notwithstanding, although there is some evidence of P. ginseng effects in humans, no evidence has been obtained respect to its supplementation in human sport performance. The aim of this study is to assess the effect of P ginseng extract supplementation on the lipid metabolism and sport performance in male endurance runners. For this purpose, the effect of supplementation for 2 weeks of 500 mg/day of P. ginseng will be evaluated in a sub-maximal physical stress test. Variables of lipid metabolism, energy consumption, fatigue, and endurance will be determined.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes.
   Hernández-García D, Granado-Serrano AB, Martín-Gari M, Ensenyat A, et al · · 2024 · PMID 38785940 · DOI 10.3390/biom14050533