Who is sponsoring NCT03872960?

NCT03872960 is sponsored by Guy's and St Thomas' NHS Foundation Trust.

What drugs are being tested in NCT03872960?

Interventions in NCT03872960: Transfer to cardiac arrest centre.

What condition does NCT03872960 study?

NCT03872960 studies Out-Of-Hospital Cardiac Arrest.

Is NCT03872960 still recruiting?

NCT03872960 is currently completed. Last updated 28 May 2024.

Last reviewed 2024-05-28 · How we verify

NCT03872960: ARREST

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest

Completed NA Last updated 28 May 2024

What this trial tests

NA trial testing Transfer to cardiac arrest centre in Out-Of-Hospital Cardiac Arrest in 862 participants. Completed in 30 April 2024.

Timeline

2 February 2018

Primary endpoint
4 December 2023

30 April 2024

Quick facts

Lead sponsor	Guy's and St Thomas' NHS Foundation Trust
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	862
Start date	2 February 2018
Primary completion	4 December 2023
Estimated completion	30 April 2024
Sites	22 locations across United Kingdom

Drugs / interventions tested

Transfer to cardiac arrest centre

Conditions studied

Out-Of-Hospital Cardiac Arrest — all drugs for Out-Of-Hospital Cardiac Arrest →

Sponsor

Guy's and St Thomas' NHS Foundation Trust

Who can join

18 and older, any sex, with Out-Of-Hospital Cardiac Arrest. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of ARREST is to determine the best post-resuscitation care pathway for out of hospital cardiac arrest patients without ST-segment elevation. The investigators propose that changes to emergency management comprising expedited delivery to a specialist heart attack centre with organised post-cardiac arrest care including immediate access to reperfusion therapy will reduce mortality in patients without STE compared to the current standard of care, which comprises protracted pre-hospital management of the patient without definitive care plan and delivery to geographically closest hospital.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Coronary Angiography in Patients With Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation on Electrocardiograms: A Comprehensive Review.
Kumar S, Abdelghaffar B, Iyer M, Shamaileh G, et al · · 2023 · cited 4× · PMID 39132520 · DOI 10.1016/j.jscai.2022.100536
Coronary Revascularization and Out-of-hospital Cardiac Arrest: Past, Present and Future.
Wa MELK, Silva K, Pareek N, Perera D. · · 2021 · PMID 36277833 · DOI 10.17925/hi.2021.15.2.94
Percutaneous Coronary Revascularization after Out-of-Hospital Cardiac Arrest: A Review of the Literature and a Case Series.
Scavelli F, Cartella I, Montalto C, Oreglia JA, et al · · 2022 · PMID 35268485 · DOI 10.3390/jcm11051395

Verify or expand the search:

Other recruiting trials for Out-Of-Hospital Cardiac Arrest

Currently open trials in the same condition.

NCT06538155 — Technological and Patient-tailored Innovations for Maximizing Effectiveness of Cardiac Arrest Resuscitation · recruiting
NCT06530433 — Enhanced Community First Responder System Evaluation in Singapore · NA · recruiting
NCT06203847 — The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA · NA · recruiting
NCT06306625 — REmote COnditioning in Out-of-Hospital Cardiac Arrest · NA · recruiting
NCT06071910 — Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest · NA · recruiting

Other Guy's and St Thomas' NHS Foundation Trust trials

Trials by the same sponsor.

NCT07534917 — Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. · not yet recruiting
NCT07454135 — Mechanisms of Atrial Pathoelectrophysiology in HCM · not yet recruiting
NCT07419945 — Older Kidney Patient Optimisation Pretransplant · NA · not yet recruiting
NCT07309835 — Improving Genetic Medicine for Ethnic Minority Groups · not yet recruiting
NCT07203872 — Inflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03872960 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Guy's and St Thomas' NHS Foundation Trust
Last refreshed: 28 May 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03872960.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing