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NCT03864536

A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions

Completed NA Results posted Last updated 29 July 2024
What this trial tests

NA trial testing Cognitive Prescriptions in Cognitive Change in 39 participants. Completed in 30 January 2022.

Timeline
1 January 2020
Primary endpoint
30 January 2022
30 January 2022

Quick facts

Lead sponsorUniversity of Alabama at Birmingham
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeprevention
Enrollment39
Start date1 January 2020
Primary completion30 January 2022
Estimated completion30 January 2022
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Alabama at Birmingham

Who can join

Adults 50 to 65, any sex, with Cognitive Change or Health Behavior. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Leisure Activities Questionnaire Activities Sum Primary · change from baseline to 3 months

The full measure is a 30-item survey asking about frequency of activities across 4 domains (cognitive, physical, social, and passive), in which higher scores reflect greater engagement in each type of activity (participants rate on Likert scale how often they perform each activity, 0=never/occasionally to 7=daily). The results below reflect a sum of cognitive, physical, and social activities (19 total activities). The total possible sum range is 0 to 133.

GroupValue95% CI
No-contact Control1.45-5.41 – 8.32
Psychoeducation Control4.45-3.23 – 12.14
Psychoeducation + CogRx11.254.10 – 18.40
Dementia Knowledge Secondary · change from baseline to 3 months

Scores on the Dementia Knowledge Assessment Scale (DKAS-27) which assesses knowledge about risk factors and prognosis of dementia. Scores include percentage correct for the 27 items, with scores ranging from 0-100%. There are 27 items and each item is scored as correct or incorrect. Therefore the scores include a percentage of total items correct, ranging from 0-100 with higher meaning better knowledge.

GroupValue95% CI
No-contact Control101 – 19
Psychoeducation Control2716 – 37
Psychoeducation + CogRx199 – 28

Sponsor's own description

The goal of this R21 study is to explore the feasibility and preliminary efficacy of individualized cognitive prescriptions (CogRxs) in improving engagement in healthy behaviors and other outcomes in middle-aged AAs and to gain feedback on future implementation of the program.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Cognitive Change

Currently open trials in the same condition.

Other University of Alabama at Birmingham trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03864536.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing