Last reviewed · How we verify
NCT03862651
Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)
Phase 2 trial testing Cangrelor in Platelet Aggregation Inhibitors in 140 participants. Status unknown.
31 December 2020
Quick facts
| Lead sponsor | Ospedale Santa Croce-Carle Cuneo |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 June 2019 |
| Primary completion | 31 December 2020 |
| Estimated completion | 1 January 2021 |
Drugs / interventions tested
- Cangrelor (CANGRELOR) — full drug profile →
Conditions studied
- Platelet Aggregation Inhibitors — all drugs for Platelet Aggregation Inhibitors →
Sponsor
Ospedale Santa Croce-Carle Cuneo — full company profile →
Who can join
18 and older, any sex, with Platelet Aggregation Inhibitors. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The MONET BRIDGE study is designed to assess the use of cangrelor as a platelet-inhibiting bridge for patients who discontinue DAPT before cardiac and non cardiac surgery within 12 months from coronary stent implantation. It seeks to determine if initiation of a prolonged cangrelor infusion maintains effective platelet inhibition after discontinuation of P2Y12 and whether a cangrelor infusion before cardiac and non cardiac procedures is safe.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Cangrelor: Clinical Data, Contemporary Use, and Future Perspectives.
De Luca L, Steg PG, Bhatt DL, Capodanno D, et al · · 2021 · cited 62× · PMID 34212768 · DOI 10.1161/jaha.121.022125 -
Intravenous antiplatelet therapies (glycoprotein IIb/IIIa receptor inhibitors and cangrelor) in percutaneous coronary intervention: from pharmacology to indications for clinical use.
Capodanno D, Milluzzo RP, Angiolillo DJ. · · 2019 · cited 49× · PMID 31823688 · DOI 10.1177/1753944719893274 -
Antiplatelet Therapy with Cangrelor in Patients Undergoing Surgery after Coronary Stent Implantation: A Real-World Bridging Protocol Experience.
Rossini R, Masiero G, Fruttero C, Passamonti E, et al · · 2020 · cited 19× · PMID 33376943 · DOI 10.1055/s-0040-1721504
Verify or expand the search:
- PubMed search for NCT03862651
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cangrelor
Trials testing the same drug.
- NCT06792643 — Cangrelor on Top of anticoagUlation in Patients With myocaRdial Infarction-related Cardiogenic Shock/Cardiac Arrest rece · Phase 2 · recruiting
- NCT05505591 — Intravenous CAngrelor in High-bleeding Risk Patients Undergoing percutaneouS Coronary Intervention (ICARUS) Registry · unknown
- NCT04667078 — REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke pat · Phase 3 · recruiting
- NCT04790032 — Pharmacodynamic Effects of Cangrelor in ACS or CCS Patients Undergoing PCI (POMPEII Registry) · completed
- NCT04668144 — Pharmacodynamic and Pharmacokinetic of Switching From Cangrelor to Prasugrel in ACS Patients Undergoing PCI · Phase 4 · completed
Other recruiting trials for Platelet Aggregation Inhibitors
Currently open trials in the same condition.
- NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
- NCT05702463 — Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II · Phase 1 · recruiting
- NCT03462498 — ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS · Phase 4 · active not recruiting
Other Ospedale Santa Croce-Carle Cuneo trials
Trials by the same sponsor.
- NCT05324150 — M Charts Versus Amsler Test in Evaluating Metamorphopsia in nAMD · completed
- NCT04037787 — ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Colorectal Cancer Surgery · NA · completed
- NCT03368612 — Comparative Study Between the AirGoTM System and Standard Tests in the Assessment of the Respiratory Function · unknown
- NCT03645018 — Lung Cancer Early Diagnosis With Digital Tomosynthesis: Re-evaluation of Lung Nodule Detection Rate at 5 Years · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03862651 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ospedale Santa Croce-Carle Cuneo
- Last refreshed: 5 March 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03862651.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing