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NCT03862651

Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)

Status unknown Phase 2 Last updated 5 March 2019
What this trial tests

Phase 2 trial testing Cangrelor in Platelet Aggregation Inhibitors in 140 participants. Status unknown.

Timeline
1 June 2019
Primary endpoint
31 December 2020
1 January 2021

Quick facts

Lead sponsorOspedale Santa Croce-Carle Cuneo
PhasePhase 2
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designsingle group
Maskingdouble
Primary purposetreatment
Enrollment140
Start date1 June 2019
Primary completion31 December 2020
Estimated completion1 January 2021

Drugs / interventions tested

Conditions studied

Sponsor

Ospedale Santa Croce-Carle Cuneo — full company profile →

Who can join

18 and older, any sex, with Platelet Aggregation Inhibitors. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The MONET BRIDGE study is designed to assess the use of cangrelor as a platelet-inhibiting bridge for patients who discontinue DAPT before cardiac and non cardiac surgery within 12 months from coronary stent implantation. It seeks to determine if initiation of a prolonged cangrelor infusion maintains effective platelet inhibition after discontinuation of P2Y12 and whether a cangrelor infusion before cardiac and non cardiac procedures is safe.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Cangrelor: Clinical Data, Contemporary Use, and Future Perspectives.
    De Luca L, Steg PG, Bhatt DL, Capodanno D, et al · · 2021 · cited 62× · PMID 34212768 · DOI 10.1161/jaha.121.022125
  2. Intravenous antiplatelet therapies (glycoprotein IIb/IIIa receptor inhibitors and cangrelor) in percutaneous coronary intervention: from pharmacology to indications for clinical use.
    Capodanno D, Milluzzo RP, Angiolillo DJ. · · 2019 · cited 49× · PMID 31823688 · DOI 10.1177/1753944719893274
  3. Antiplatelet Therapy with Cangrelor in Patients Undergoing Surgery after Coronary Stent Implantation: A Real-World Bridging Protocol Experience.
    Rossini R, Masiero G, Fruttero C, Passamonti E, et al · · 2020 · cited 19× · PMID 33376943 · DOI 10.1055/s-0040-1721504

Verify or expand the search:

Other trials of Cangrelor

Trials testing the same drug.

Other recruiting trials for Platelet Aggregation Inhibitors

Currently open trials in the same condition.

Other Ospedale Santa Croce-Carle Cuneo trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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