Last reviewed · How we verify
NCT03859063: LAST-long
Long-term Follow-up After Stroke (The LAST-long Trial)
NA trial testing Intervention in Stroke in 301 participants. Completed in 31 December 2024.
30 September 2024
Quick facts
| Lead sponsor | Norwegian University of Science and Technology |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 301 |
| Start date | 11 April 2019 |
| Primary completion | 30 September 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 4 locations across Norway |
Drugs / interventions tested
- Intervention
- Control
Conditions studied
- Stroke — all drugs for Stroke →
Sponsor
Norwegian University of Science and Technology
Who can join
18 and older, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Despite the improved treatment of acute stroke over the past decades, those suffering from stroke still are at an increased risk of functional and cognitive decline in the long term. The most common consequences of stroke are functional impairments, cognitive impairments, depression and fatigue. These are also regarded as barriers to achieve optimal adherence to the guidelines regarding secondary prevention. The primary aim of this project is to evaluate the effectiveness of a multimodal individualized intervention to prevent functional decline in the long term after stroke.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Late Breaking Abstracts.
· 2021 · cited 10× · PMID 35252583 · DOI 10.1177/23969873211044666 -
Multimodal individualised intervention to prevent functional decline after stroke: protocol of a randomised controlled trial on long-term follow-up after stroke (LAST-long).
Askim T, Hokstad A, Bergh E, Døhl Ø, et al · · 2023 · cited 4× · PMID 37164457 · DOI 10.1136/bmjopen-2022-069656 -
A multimodal individualized long-term intervention to prevent functional decline after stroke (LAST-long): a single blinded randomised controlled trial.
Askim T, Langlo SR, Bergh E, Døhl Ø, et al · · 2026 · cited 1× · PMID 41323876 · DOI 10.1016/j.lanepe.2025.101531 -
11th European Stroke Organisation Conference Abstracts - 21-23 May 2025, Helsinki, Finland: Late Breaking Abstracts.
· 2025 · cited 1× · PMID 40726473 · DOI 10.1177/23969873251345751 -
Reduced physical activity level was associated with poorer quality of life during the early phase of the COVID-19 pandemic: a sub-study of the last-long trial.
Hokstad A, Thommessen B, Ihle-Hansen H, Indredavik B, et al · · 2023 · cited 1× · PMID 38058014 · DOI 10.2340/jrm.v55.12352 -
ESOC 2023 Abstract Book
· 2023 -
ESOC 2022 Abstract Book
· 2022 -
ESOC 2022 – Late Breaking Science, Ongoing Trials & Young Stroke Physicians and Researchers
· 2022
Verify or expand the search:
- PubMed search for NCT03859063
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Norwegian University of Science and Technology trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03859063 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Norwegian University of Science and Technology
- Last refreshed: 16 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03859063.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing