Last reviewed · How we verify
NCT03853226: VPLOOP
Rational for the Use of Velocity-Pressure Loop in the Operating Room
trial testing All monitoring in Radiography in 55 participants. Completed in 25 March 2016.
25 January 2016
Quick facts
| Lead sponsor | Joaquim MATEO |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 55 |
| Start date | 5 January 2014 |
| Primary completion | 25 January 2016 |
| Estimated completion | 25 March 2016 |
Drugs / interventions tested
- All monitoring
Conditions studied
- Radiography — all drugs for Radiography →
- Interventional — all drugs for Interventional →
Sponsor
Joaquim MATEO
Who can join
18 and older, any sex, with Radiography or Interventional. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In surgical patients considered with "high cardiovascular risk", by their field or by the nature of their intervention, it is recommended to use hemodynamic monitoring including a continuous measurement device of arterial pressure and cardiac output (CO). However, targeting mean arterial pressure (MAP) with boluses of selective peripheral vasopressors (without positive inotropic or chronotropic effects) could have deleterious effects on CO. Thus, it seems important to use a combined analysis of MAP and CO to estimate the afterload-related cardiac performance (ACP) The investigators recently proposed a cardiac afterload monitoring, in the descending thoracic aorta, based on a combined analysis of flow velocity signal recorded by trans-oesophageal Doppler and aortic pressure, the Velocity-Pressure Loop (VP Loop). VP Loop, and its derived indicators, especially Global AfterLoad Angle (GALA), could be useful during hemodynamic management for continuous cardiac afterload monitoring. However, in cardiology unit, cardiac afterload is usually measured at the ascending aorta behind the aortic valves. The main objective of this study is to compare VP Loop parameters build in the ascending and descending thoracic aorta according to patient cardiovascular risk factors.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03853226
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of All monitoring
Trials testing the same drug.
- NCT03756935 — Early Detection of Intra Operative Hypotension (IOH) During the Induction of General Anaesthesia · completed
- NCT03769142 — Cerebral Perfusion During Induction of General Anesthesia · completed
Other recruiting trials for Radiography
Currently open trials in the same condition.
- NCT07200011 — Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures · active not recruiting
Other Joaquim MATEO trials
Trials by the same sponsor.
- NCT03876379 — Brain Power Spectral Density Under Propofol · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03853226 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Joaquim MATEO
- Last refreshed: 27 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03853226.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing