Last reviewed · How we verify
NCT03829189
High-fiber Diet on the Body and the Brain
NA trial testing inulin in Diet Modification in 61 participants. Completed in 24 November 2020.
24 November 2020
Quick facts
| Lead sponsor | Max Planck Institute for Human Cognitive and Brain Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 61 |
| Start date | 14 January 2019 |
| Primary completion | 24 November 2020 |
| Estimated completion | 24 November 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- inulin — full drug profile →
- maltodextrin (MALTODEXTRIN) — full drug profile →
Conditions studied
- Diet Modification — all drugs for Diet Modification →
- Overweight — all drugs for Overweight →
Sponsor
Max Planck Institute for Human Cognitive and Brain Sciences
Who can join
Adults 18 to 45, any sex, with Diet Modification or Overweight. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The central research question aims to understand what drives individuals to make and maintain a vegan / vegetarian dietary decision, to investigate whether there are possible predictors that might influence such a decision and whether personality differences already exist or can only be measured after the change in diet. The investigators will examine the effects of a high-fiber diet on food wanting on a neural and on a behavioral level. The microbiome is suggested to mediate the expected changes in food wanting.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior.
Medawar E, Haange SB, Rolle-Kampczyk U, Engelmann B, et al · · 2021 · cited 94× · PMID 34599144 · DOI 10.1038/s41398-021-01620-3 -
Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial.
Medawar E, Beyer F, Thieleking R, Haange SB, et al · · 2024 · cited 33× · PMID 37793780 · DOI 10.1136/gutjnl-2023-330365 -
Nutrient scoring for the DEGS1-FFQ - from food intake to nutrient intake.
Thieleking R, Schneidewind L, Kanyamibwa A, Hartmann H, et al · · 2023 · cited 19× · PMID 36639712 · DOI 10.1186/s40795-022-00636-2
Verify or expand the search:
- PubMed search for NCT03829189
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of inulin
Trials testing the same drug.
- NCT07189585 — Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis · Phase 2 · not yet recruiting
- NCT07112248 — Effects of Soluble Fiber Supplements on Sperm Quality in Males With Obesity: a Randomized Trial · NA · not yet recruiting
- NCT06551961 — Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation · NA · recruiting
- NCT06420401 — Prebiotics and the Management of Hyperuricemia · NA · recruiting
- NCT06404749 — Fungal Fiber for Gut Health · NA · terminated
Other recruiting trials for Diet Modification
Currently open trials in the same condition.
- NCT07086833 — The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities · NA · recruiting
- NCT06882252 — Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes · NA · recruiting
- NCT06723028 — Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls · NA · recruiting
- NCT06714656 — Drivers and Barriers for Adopting Healthy and Sustainable Food Swaps in Young · NA · recruiting
- NCT06365684 — Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 · Phase 4 · recruiting
Other Max Planck Institute for Human Cognitive and Brain Sciences trials
Trials by the same sponsor.
- NCT07501377 — Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living Wit · NA · recruiting
- NCT06116942 — Magnetic Brain Stimulation and Computer-based Motor Training for Rehabilitation After Stroke · NA · recruiting
- NCT05232955 — Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI · completed
- NCT05233306 — Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 2: 7T MRI · completed
- NCT06729658 — Dopamine and Brain Computer Interface · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03829189 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Max Planck Institute for Human Cognitive and Brain Sciences
- Last refreshed: 27 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03829189.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing