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NCT03827915
Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion
NA trial testing Double sequential external defibrillation in Atrial Fibrillation in 100 participants. Status unknown.
21 January 2024
Quick facts
| Lead sponsor | American University of Beirut Medical Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 21 January 2019 |
| Primary completion | 21 January 2024 |
| Estimated completion | 21 January 2024 |
| Sites | 1 location across Lebanon |
Drugs / interventions tested
- Double sequential external defibrillation
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Defibrillators — all drugs for Defibrillators →
- Persistent Atrial Fibrillation — all drugs for Persistent Atrial Fibrillation →
Sponsor
American University of Beirut Medical Center
Who can join
Eligibility, any sex, with Atrial Fibrillation or Defibrillators. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Atrial fibrillation (AF) is a common cardiac arrhythmia that leads to increased risk of heart failure, hospitalization, thromboembolic events, and death. Restoration of normal heart rhythm is performed in many patients with AF to improve symptoms. In this study, the investigators will consider patients who fail 2 or more trials of DC cardioversion as having refractory AF. The aim of this study is to assess whether the use of double sequential defibrillation in patients with refractory AF has a higher success rate in reverting them to a normal heart rhythm than a third cardioversion. This is a phase III, randomized controlled, single-centered, superiority trial. All patients with AF admitted to the coronary care unit (CCU) for DC cardioversion, and refractory to at least two trials of DC cardioversion will be enrolled. Patients are randomized into two arms: the first will receive a third trial of DC cardioversion (standard of care) and the second will receive double sequential external defibrillation. The resolution of AF by reverting back to normal sinus rhythm is the primary outcome of the investigators. This will be determined using EKG (electrocardiogram) immediately after DC cardioversion or double sequential defibrillation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03827915
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03827915 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by American University of Beirut Medical Center
- Last refreshed: 4 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03827915.
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