NCT03824639

Exercise Training to Improve Cognitive Function

Completed NA Results posted Last updated 14 February 2024

What this trial tests

NA trial testing Structured exercise in Mild Cognitive Impairment in 60 participants. Completed in 31 July 2022.

Timeline

23 April 2019

Primary endpoint
31 May 2022

31 July 2022

Quick facts

Lead sponsor	VA Office of Research and Development
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	60
Start date	23 April 2019
Primary completion	31 May 2022
Estimated completion	31 July 2022
Sites	1 location across United States

Drugs / interventions tested

• Structured exercise
• Health Education

Conditions studied

• Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →

Sponsor

VA Office of Research and Development — full company profile →

Who can join

50 and older, any sex, with Mild Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change in Delayed Recall Score on Wechsler Logical Memory Task From Baseline to 6 Months Primary · baseline and 6 months

Wechsler Logical Memory Task is a recall test involving 2 short stories. Possible scores on the delayed recall task range from 0 (no details recalled for both stories) to 50 (all details recalled on both stories). Outcome is change in the delayed recall score from baseline to 6 months.

Group	Value	95% CI
Exercise Group	0.74	± 4.0
Control Group	-0.87	± 4.7

Change in Delayed Recall Score on the Rey-Osterrieth Complex Figure Test From Baseline to 6 Months Secondary · baseline and 6 months

Rey-Osterrieth Complex Figure Test is a recall test involving a complex figure. Possible scores on the delayed recall task range from 0 (no accurate details recalled for the figure) to 36 (all details accurately recalled for the figure). Outcome is change in the delayed recall score from baseline to 6 months.

Group	Value	95% CI
Exercise Group	1.18	± 4.5
Control Group	0.46	± 3.3

Sponsor's own description

This project is assessing the feasibility of a novel home-based exercise intervention to improve episodic memory in individuals with mild cognitive impairment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.