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NCT03819088
Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer
NA trial testing Zinc in Gastric Carcinoma in 17 participants. Completed in 22 March 2022.
5 October 2021
Quick facts
| Lead sponsor | Emory University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 17 |
| Start date | 17 April 2019 |
| Primary completion | 5 October 2021 |
| Estimated completion | 22 March 2022 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Zinc — full drug profile →
Conditions studied
- Gastric Carcinoma — all drugs for Gastric Carcinoma →
- Liver and Intrahepatic Bile Duct Carcinoma — all drugs for Liver and Intrahepatic Bile Duct Carcinoma →
- Unresectable Esophageal Carcinoma — all drugs for Unresectable Esophageal Carcinoma →
- Unresectable Pancreatic Carcinoma — all drugs for Unresectable Pancreatic Carcinoma →
Sponsor
Emory University
Who can join
Eligibility, any sex, with Gastric Carcinoma or Liver and Intrahepatic Bile Duct Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized study examines how well zinc works in improving quality of life in patients with gastrointestinal cancer that cannot be removed by surgery who are receiving chemotherapy. Zinc may help to improve patient's quality of life by preventing zinc deficiency.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets.
Chen B, Yu P, Chan WN, Xie F, et al · · 2024 · cited 195× · PMID 38169461 · DOI 10.1038/s41392-023-01679-y -
The Human Microbiomes in Pancreatic Cancer: Towards Evidence-Based Manipulation Strategies?
Brandi G, Turroni S, McAllister F, Frega G. · · 2021 · cited 15× · PMID 34576078 · DOI 10.3390/ijms22189914 -
Micronutrient Food Supplements in Patients with Gastro-Intestinal and Hepatic Cancers.
Alam W, Ullah H, Santarcangelo C, Di Minno A, et al · · 2021 · cited 7× · PMID 34360782 · DOI 10.3390/ijms22158014
Verify or expand the search:
- PubMed search for NCT03819088
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Zinc
Trials testing the same drug.
- NCT06664008 — The Effect of Probiotic and Zinc Supplementation in Patients With Gastroesophageal Reflux Disease · Phase 4 · not yet recruiting
- NCT06540209 — Comparison of Effectiveness of Zinc Supplementation With ORS and Bacillus Clausii Versus Zinc With ORS and Saccharomyces · NA · completed
- NCT05785013 — The Impact of Preoperative Supplementation of Zinc · NA · completed
- NCT05212480 — Evaluation of the Efficacy and Safety of Zinc in Viral Infections · NA · completed
- NCT05453227 — Zinc Containing Vaginal Topical " Suppository " · Phase 1, PHASE2 · completed
Other recruiting trials for Gastric Carcinoma
Currently open trials in the same condition.
- NCT07283939 — Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays · NA · recruiting
- NCT07315750 — A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab Wi · Phase 3 · recruiting
- NCT07139418 — The Clinical Significance of Examining Metastatic Lymph Nodes in Individual Gastric Mesenteries in the Patients With Gas · recruiting
- NCT07108855 — Detection of Upper Gastrointestinal Tumour Depth and Demarcation Using Systemic Administration of Indocyanine Green Duri · Phase 1, PHASE2 · recruiting
- NCT07118176 — Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers · Phase 1 · recruiting
Other Emory University trials
Trials by the same sponsor.
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- NCT07189819 — Innovative Closed-loop Functional Electrical Stimulation Control System for Augmenting Post-stroke Gait · NA · not yet recruiting
- NCT06451055 — Low-calorie Diet in Isolated Impaired Fasting Glucose · NA · not yet recruiting
- NCT07405476 — Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative I · Phase 2 · recruiting
- NCT06708351 — Enhancing Cervical Cancer Screening and Treatment in Women Living With HIV in Kenya, the ENHANCE LINKAge Trial · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03819088 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Emory University
- Last refreshed: 9 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03819088.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing