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NCT03816293: SUpPressSSI
SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections
NA trial testing Negative Pressure Wound Therapy in Surgical Site Infection in 3,680 participants. Completed in 30 September 2021.
31 March 2021
Quick facts
| Lead sponsor | University of Illinois at Chicago |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | sequential |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 3,680 |
| Start date | 1 May 2019 |
| Primary completion | 31 March 2021 |
| Estimated completion | 30 September 2021 |
| Sites | 5 locations across United States |
Drugs / interventions tested
- Negative Pressure Wound Therapy
Conditions studied
- Surgical Site Infection — all drugs for Surgical Site Infection →
- Obesity — all drugs for Obesity →
- Diabetes — all drugs for Diabetes →
- Cesarean Section Complications — all drugs for Cesarean Section Complications →
Sponsor
University of Illinois at Chicago
Who can join
18 and older, any sex, with Surgical Site Infection or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our goal is to provide data that will give surgeons and hospitals clear recommendations on the use of NPWT for Cesarean section, abdominal hysterectomy and colon surgeries in patients with diabetes and/or obesity. We also want to understand the patient experience with the dressing so that we can provide information that will enable clinicians to remove barriers to NPWT use. Additionally, we are seeking to use automated electronic medical record decision support to identify patients that will benefit most from the NPWT.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Shi C, Goh EL, Murphy EM, et al · · 2022 · cited 71× · PMID 35471497 · DOI 10.1002/14651858.cd009261.pub7 -
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Goh EL, Dumville JC, Shi C, et al · · 2020 · cited 48× · PMID 32542647 · DOI 10.1002/14651858.cd009261.pub6 -
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Goh EL, Dumville JC, Shi C, et al · · 2020 · cited 38× · PMID 32356396 · DOI 10.1002/14651858.cd009261.pub5
Verify or expand the search:
- PubMed search for NCT03816293
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Negative Pressure Wound Therapy
Trials testing the same drug.
- NCT06832787 — Evaluation of Combinational Use of Negative Pressure Wound Therapy (NPWT) for Diabetic Foot Wounds · NA · recruiting
- NCT06957964 — Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial · NA · recruiting
- NCT06873867 — Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone · NA · completed
- NCT07258134 — Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing · NA · completed
- NCT06647290 — ENVELOP: Wound Care Following Pilonidal Sinus Surgery · NA · recruiting
Other recruiting trials for Surgical Site Infection
Currently open trials in the same condition.
- NCT07501897 — Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Followin · NA · recruiting
- NCT07311395 — Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section · NA · recruiting
- NCT06649890 — A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™ · NA · recruiting
- NCT07005635 — The Effects of Different Time Reminder On Surgical Hand Scrubing · NA · active not recruiting
- NCT07049614 — Comparative Study of Postoperative Surgical Site Infections in Diabetic and Non-Diabetic Patients · active not recruiting
Other University of Illinois at Chicago trials
Trials by the same sponsor.
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- NCT07504120 — The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03816293 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Chicago
- Last refreshed: 21 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03816293.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing