Last reviewed · How we verify
NCT07258134
Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing
NA trial testing Negative Pressure Wound Therapy in Negative-Pressure Wound Therapy in 72 participants. Completed in 30 August 2025.
30 August 2025
Quick facts
| Lead sponsor | Sindh Institute of Urology and Transplantation |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 72 |
| Start date | 24 February 2025 |
| Primary completion | 30 August 2025 |
| Estimated completion | 30 August 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Negative Pressure Wound Therapy
Conditions studied
- Negative-Pressure Wound Therapy — all drugs for Negative-Pressure Wound Therapy →
- Wound Heal — all drugs for Wound Heal →
- Stoma Site Infection — all drugs for Stoma Site Infection →
- Surgical Site Infection — all drugs for Surgical Site Infection →
Sponsor
Sindh Institute of Urology and Transplantation
Who can join
Adults 18 to 80, any sex, with Negative-Pressure Wound Therapy or Wound Heal. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This was a single-center, parallel-group randomized controlled trial conducted in 2024 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi. The study compared negative pressure wound therapy (NPWT) with healing by secondary intention (SIH) for patients undergoing stoma reversal surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07258134
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Negative Pressure Wound Therapy
Trials testing the same drug.
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- NCT06873867 — Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone · NA · completed
- NCT06647290 — ENVELOP: Wound Care Following Pilonidal Sinus Surgery · NA · recruiting
- NCT06758258 — Negative Pressure Wound Therapy in Oral Surgery · NA · completed
Other Sindh Institute of Urology and Transplantation trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07258134 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sindh Institute of Urology and Transplantation
- Last refreshed: 2 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07258134.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing