NCT03815045

Ultrasound Guided Diagnostic Lumbar Puncture in Neurology

Terminated NA Last updated 31 January 2024

What this trial tests

NA trial testing Landmark-based lumbar puncture in Lumbar Puncture in 38 participants. Terminated before completion.

Timeline

20 July 2017

Primary endpoint
10 March 2023

31 December 2023

Quick facts

Lead sponsor	Dartmouth-Hitchcock Medical Center
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	38
Start date	20 July 2017
Primary completion	10 March 2023
Estimated completion	31 December 2023
Sites	1 location across United States

Drugs / interventions tested

• Landmark-based lumbar puncture
• Ultrasound-guided lumbar puncture

Conditions studied

• Lumbar Puncture — all drugs for Lumbar Puncture →

Sponsor

Dartmouth-Hitchcock Medical Center

Who can join

18 and older, any sex, with Lumbar Puncture. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Subjects who are having a lumbar puncture as part of their clinical care will be randomized to either a traditional landmark based lumbar puncture or ultrasound guided lumbar puncture. The primary objective of study is to compare the success rate of obtaining CSF using Ultrasound guided technique against the Traditional Landmark based approach. Secondary objectives are to evaluate factors influencing the success or failure, patient tolerance, and a safety assessment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. 'UltraGUD LP'-ultrasound guided diagnostic LP-a randomizedcontrolled trial. Traditional landmark based lumbar puncture is as effective as ultrasound guided lumbar puncture in outpatient neurology settings.
   Renga V, Jeffreys CA, Tabasum A, MacKenzie TA. · · 2025 · PMID 40134695 · DOI 10.3389/fneur.2025.1521783