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NCT03812601: BiMap-AF
Biatrial Global High-density Electroanatomical Mapping of Atrial Fibrillation
trial testing Simultaneous bi-atrial electroanatomic mapping and ablation in Atrial Fibrillation in 22 participants. Completed in 10 November 2021.
10 September 2020
Quick facts
| Lead sponsor | Oxford University Hospitals NHS Trust |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 22 |
| Start date | 11 October 2018 |
| Primary completion | 10 September 2020 |
| Estimated completion | 10 November 2021 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Simultaneous bi-atrial electroanatomic mapping and ablation
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
Oxford University Hospitals NHS Trust
Who can join
18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study uses two AcQMap imaging and electroanatomical mapping systems (Acutus Medical) to simultaneously visualise and map patterns of wavefront propagation in both the left and right atria during atrial fibrillation in order to identify mechanisms of rhythm propagation and maintenance and the importance of the interaction of the left and right atria. Mapping will also be performed during pacing from different sites and cycle lengths to identify regions of abnormal conduction that may be related to the maintenance of atrial fibrillation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Spatial and temporal variability of rotational, focal, and irregular activity: Practical implications for mapping of atrial fibrillation.
Pope MT, Kuklik P, Briosa E Gala A, Leo M, et al · · 2021 · cited 19× · PMID 34260134 · DOI 10.1111/jce.15170 -
Impact of Adenosine on Wavefront Propagation in Persistent Atrial Fibrillation: Insights From Global Noncontact Charge Density Mapping of the Left Atrium.
Pope MTB, Kuklik P, Briosa E Gala A, Leo M, et al · · 2022 · cited 9× · PMID 35621197 · DOI 10.1161/jaha.121.021166
Verify or expand the search:
- PubMed search for NCT03812601
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
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- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other Oxford University Hospitals NHS Trust trials
Trials by the same sponsor.
- NCT07303582 — Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities · Phase 4 · recruiting
- NCT06922695 — Responding to AF: Pill-in-Pocket Anticoagulation Guided by Automated Monitoring and Alerts · NA · recruiting
- NCT06822686 — Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease · NA · not yet recruiting
- NCT06397664 — The Impact of Chronic Adolescent Skin Conditions on Sexual Health · completed
- NCT06130397 — AI Assisted Detection of Fractures on X-Rays (FRACT-AI) · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03812601 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oxford University Hospitals NHS Trust
- Last refreshed: 19 January 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03812601.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing