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NCT03812419
Esomeprazole or Pantoprazole in Renal Transplantation
NA trial testing Esomeprazole 40 mg in Kidney Transplant; Complications in 47 participants. Completed in 30 December 2016.
10 December 2016
Quick facts
| Lead sponsor | Future University in Egypt |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 47 |
| Start date | 5 January 2016 |
| Primary completion | 10 December 2016 |
| Estimated completion | 30 December 2016 |
Drugs / interventions tested
- Esomeprazole 40 mg — full drug profile →
- Pantoprazole 40mg — full drug profile →
Conditions studied
- Kidney Transplant; Complications — all drugs for Kidney Transplant; Complications →
Sponsor
Future University in Egypt
Who can join
Adults 18 to 65, any sex, with Kidney Transplant; Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
prospective, parallel, open-label clinical trial was performed on forty-seven adult renal transplant recipients receiving immunosuppressive therapy with CsA doses adjusted to attain trough concentrations of 100-150 μg/L, mycophenolate mofetil (MMF) at 750 mg q12 hr and prednisolone at 5 mg daily randomized into two groups, which received esomeprazole or pantoprazole at the same dose (40 mg once daily). To compare the influence of pantoprazole and esomeprazole on serum cyclosporine (CsA) levels in stable renal transplant recipients.Cyclosporine (C0), renal function and complete blood count were measured at baseline and for 6 months. Main outcome measures Clinical signs of rejection and renal function decline, assessed by serum creatinine elevations, caused by CsA level variations in either of the study groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03812419
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Future University in Egypt trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03812419 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Future University in Egypt
- Last refreshed: 24 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03812419.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing