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NCT03803176
Tissue Plasminogen Activator & Plasminogen Activator Inhibitor Type-1 In Gingival Tissues Of Chronic Periodontitis
trial testing Open Flap Debridement in Chronic Periodontitis in 30 participants. Completed in 14 August 2018.
11 June 2018
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 12 February 2018 |
| Primary completion | 11 June 2018 |
| Estimated completion | 14 August 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Open Flap Debridement — full drug profile →
Conditions studied
- Chronic Periodontitis — all drugs for Chronic Periodontitis →
Sponsor
Cairo University
Who can join
Adults 30 to 50, any sex, with Chronic Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Tissue Plasminogen Activator and Plasminogen Activator Inhibitor Type-1 Gene Expression will be evaluated clinically and histopathologically through Hematoxylin and eosin as well as by quantitative reverse transcription polymerase chain reaction in the gingival tissues of chronic periodontitis in an attempt to investigate whether the expression of these proteins could be involved in the disease pathogenesis or not, and to assess as well if their expression will be affected by the applied surgical periodontal treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03803176
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Open Flap Debridement
Trials testing the same drug.
- NCT07395726 — Impact of Platelet-Rich Fibrin on Periodontal Tissue Regeneration · NA · completed
- NCT05936450 — Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts · Phase 4 · completed
Other recruiting trials for Chronic Periodontitis
Currently open trials in the same condition.
- NCT06893107 — Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study. · NA · recruiting
- NCT05275192 — Utilization of a Videoscope in Periodontal Regeneration · NA · recruiting
- NCT03741374 — Minimally-invasive Non-surgical Therapy of Intrabony Defects · NA · active not recruiting
- NCT03553095 — Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis · NA · active not recruiting
Other Cairo University trials
Trials by the same sponsor.
- NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
- NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03803176 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 14 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03803176.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing