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NCT03793062

Genetic and Epigenetic Basis of Chronic Wounds

Recruiting now Last updated 14 April 2026
What this trial tests

trial testing No Interventions in Chronic Wounds in 256 participants. Currently enrolling.

Timeline
4 December 2018
Primary endpoint
1 June 2028
31 December 2028

Quick facts

Lead sponsorUniversity of Pittsburgh
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment256
Start date4 December 2018
Primary completion1 June 2028
Estimated completion31 December 2028
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Pittsburgh

Who can join

Adults 18 to 100, any sex, with Chronic Wounds. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This pilot study is designed for chronic wounds that fail to heal in a timely manner carry specific genetic signatures. These genetic signatures will be studied using debrided wound tissue that is removed by the wound care provider as part of standard of care. The reference genomic signature will be evaluated by obtaining blood samples and will be compared with wound debrided tissue genomic signature to understand wound specific genomic changes.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Epigenetic Research in Stem Cell Bioengineering-Anti-Cancer Therapy, Regenerative and Reconstructive Medicine in Human Clinical Trials.
    Dompe C, Janowicz K, Hutchings G, Moncrieff L, et al · · 2020 · cited 9× · PMID 32326172 · DOI 10.3390/cancers12041016
  2. Development and validation of the DHIS2 platform for integrating sociomedical data to study wound care outcomes.
    Paddo AR, Kodela S, Timsina L, Mathew-Steiner SS, et al · · 2024 · cited 1× · PMID 39630628 · DOI 10.1371/journal.pone.0308553

Verify or expand the search:

Other trials of No Interventions

Trials testing the same drug.

Other recruiting trials for Chronic Wounds

Currently open trials in the same condition.

Other University of Pittsburgh trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03793062.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing