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NCT03791723: APART-AF
Effect of ARNI in Patients With Persistent AF and Enlarged Left Atrium After Catheter Ablation
NA trial testing Sacubitril-Valsartan in Atrial Fibrillation in 90 participants. Status unknown.
1 January 2021
Quick facts
| Lead sponsor | The Second Affiliated Hospital of Chongqing Medical University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 1 June 2019 |
| Primary completion | 1 January 2021 |
| Estimated completion | 30 December 2021 |
Drugs / interventions tested
- Sacubitril-Valsartan — full drug profile →
- Valsartan (VALSARTAN) — full drug profile →
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Cardiac Remodeling, Atrial — all drugs for Cardiac Remodeling, Atrial →
- Sacubitril/Valsartan — all drugs for Sacubitril/Valsartan →
Sponsor
The Second Affiliated Hospital of Chongqing Medical University
Who can join
Adults 18 to 80, any sex, with Atrial Fibrillation or Cardiac Remodeling, Atrial. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this clinical randomized trial is to evaluate the efficacy and safety of Sacubitril/Valsartan compared with ARB in improving cardiac remodeling in patients With Enlarged Left Atrium Diameter and Persistent AF.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03791723
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Sacubitril-Valsartan
Trials testing the same drug.
- NCT04637152 — Sacubitril/Valsartan in Resistant Hypertension · Phase 2 · completed
- NCT04498780 — Hemodynamic Effects of ARNI on Noninvasive Pressure-volume Analysis in Patients With Chronic Heart Failure · completed
- NCT04575675 — Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy · Phase 4 · completed
- NCT04128891 — Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction · Phase 3 · withdrawn
- NCT04688294 — The Bio-Clinical Effects of the (Sacubitril-Valsartan) Combination on Patients With Chronic Heart Failure · Phase 4 · completed
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
- NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
- NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other The Second Affiliated Hospital of Chongqing Medical University trials
Trials by the same sponsor.
- NCT07534046 — Impact of Metabolic Disorders on cACLD Outcomes · not yet recruiting
- NCT07465003 — Cohort Study of Chronic Liver Disease Complicated by Sepsis · not yet recruiting
- NCT07339644 — Functional Lung Avoidance Radiotherapy Guided by 4DCT Pulmonary Ventilation Function Imaging: A Prospective Single-arm C · NA · recruiting
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- NCT07033949 — Effect of Green Light Exposure at Different Times on the Pain of Subjects · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03791723 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Second Affiliated Hospital of Chongqing Medical University
- Last refreshed: 19 March 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03791723.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing