NCT03778476 is a NA clinical trial of Isometric Exercise in Fibromyalgia, sponsored by Marquette University.

Who is sponsoring NCT03778476?

NCT03778476 is sponsored by Marquette University.

What drugs are being tested in NCT03778476?

Interventions in NCT03778476: Isometric Exercise.

What condition does NCT03778476 study?

NCT03778476 studies Fibromyalgia.

Is NCT03778476 still recruiting?

NCT03778476 is currently completed. Last updated 24 February 2021.

Last reviewed 2021-02-24 · How we verify

NCT03778476

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Isometric Exercise and Endogenous Pain Inhibition

Completed NA Last updated 24 February 2021

What this trial tests

NA trial testing Isometric Exercise in Fibromyalgia in 43 participants. Completed in 29 October 2019.

Timeline

25 May 2018

Primary endpoint
29 September 2019

29 October 2019

Quick facts

Lead sponsor	Marquette University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	43
Start date	25 May 2018
Primary completion	29 September 2019
Estimated completion	29 October 2019
Sites	1 location across United States

Drugs / interventions tested

Isometric Exercise

Conditions studied

Fibromyalgia — all drugs for Fibromyalgia →

Sponsor

Marquette University

Who can join

Adults 18 to 75, any sex, with Fibromyalgia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to identify the acute effects of isometric exercise on the inhibition of pain in individuals with fibromyalgia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Impaired conditioned pain modulation was restored after a single exercise session in individuals with and without fibromyalgia.
Alsouhibani A, Hoeger Bement M. · · 2022 · cited 11× · PMID 35399187 · DOI 10.1097/pr9.0000000000000996

Verify or expand the search:

Other trials of Isometric Exercise

Trials testing the same drug.

NCT07383220 — Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure · NA · recruiting
NCT06282302 — Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People · NA · unknown
NCT04936022 — Isometric Exercise for People With Raised Blood Pressure · NA · completed
NCT03758027 — CARESS: An Investigation of Effects of CARESS · NA · completed
NCT03262181 — The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patel · NA · completed

Other recruiting trials for Fibromyalgia

Currently open trials in the same condition.

NCT02285868 — ATI Evidence-based Guide Investigating Clinical Services · active not recruiting
NCT07245303 — Neural Mechanisms of Light Driven Analgesia · NA · recruiting
NCT05901259 — The EXOPULSE Study - a Database for Routine Follow-up of Clinical Outcomes · recruiting
NCT07358754 — The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor · recruiting
NCT07465991 — The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia · NA · recruiting

Other Marquette University trials

Trials by the same sponsor.

NCT07372183 — Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers · not yet recruiting
NCT06624982 — Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation · recruiting
NCT06858293 — Mental Imagery to Improve Quadriceps Strength Post Anterior Cruciate Ligament Reconstruction: a Feasibility Study · NA · recruiting
NCT06734052 — Computer-guided Action Planning to Support Physical Activity (CAPPA) for Employees With Chronic Knee Symptoms · NA · completed
NCT06340893 — Exercise Training in Children With Communication Impairments · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03778476 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Marquette University
Last refreshed: 24 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03778476.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing