NCT03773419: T-WRITE

Improving Electronic Written Communication in Aphasia

Completed NA Last updated 26 October 2022

What this trial tests

NA trial testing Texting Intervention (T-WRITE) in Aphasia in 63 participants. Completed in 30 September 2022.

Timeline

20 September 2018

Primary endpoint
13 August 2021

30 September 2022

Quick facts

Lead sponsor	Shirley Ryan AbilityLab
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	63
Start date	20 September 2018
Primary completion	13 August 2021
Estimated completion	30 September 2022
Sites	2 locations across United States

Drugs / interventions tested

• Texting Intervention (T-WRITE)
• HandWriting Intervention (ORLA+WTG)

Conditions studied

• Aphasia — all drugs for Aphasia →

Sponsor

Shirley Ryan AbilityLab — full company profile →

Who can join

18 and older, any sex, with Aphasia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

People with aphasia have difficulty with writing and often struggle to use electronic communication that connects people to one another. The goal of this project is to evaluate the extent to which a novel treatment (T-WRITE) improves written language function and the use of text messaging; we also evaluate whether there are subsequent positive effects on the participant's social connectedness and ultimately health-related quality of life (HRQOL).

T-WRITE involves choral reading and repeated writing of sentences via texting. Participants work intensively and independently at home on a laptop computer. A virtual therapist directs the participant to practice copying and independently writing phrases and short sentences using the typing feature on a cellular phone. The specific objective of this randomized clinical trial is to compare T-WRITE to ORLA+WTG, a similar treatment that targets written expression using handwriting.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Texting Behaviors of Individuals With Chronic Aphasia: A Descriptive Study.
   Kinsey LE, Lee JB, Larkin EM, Cherney LR. · · 2022 · cited 9× · PMID 34061572 · DOI 10.1044/2021_ajslp-20-00287
2. Transactional Success in the Texting of Individuals With Aphasia.
   Lee JB, Cherney LR. · · 2022 · cited 6× · PMID 35623321 · DOI 10.1044/2022_ajslp-21-00291
3. Validity and Reliability of the Transactional EXchanges in Texting for Aphasia Rating Scale.
   Lee JB, Azios JH, Fergadiotis G, McMahon MF, et al · · 2025 · cited 1× · PMID 41159821 · DOI 10.1044/2025_jslhr-25-00086