Who is sponsoring NCT03770026?

NCT03770026 is sponsored by Benha University.

What drugs are being tested in NCT03770026?

Interventions in NCT03770026: clomiphene citrate, Saline cervical flushing, Intrauterine Autologous platelet-rich plasma.

What condition does NCT03770026 study?

NCT03770026 studies Infertility, Female, Associated With Anovulation.

Is NCT03770026 still recruiting?

NCT03770026 is currently completed. Last updated 29 April 2020.

Last reviewed 2020-04-29 · How we verify

NCT03770026

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Autologous Platelet-rich Plasma for Clomiphene Citrate-induced Thin Endometrium

Completed Phase 2, PHASE3 Last updated 29 April 2020

What this trial tests

Phase 2, PHASE3 trial testing clomiphene citrate in Infertility, Female, Associated With Anovulation in 30 participants. Completed in 1 January 2020.

Timeline

1 January 2018

Primary endpoint
1 January 2019

1 January 2020

Quick facts

Lead sponsor	Benha University
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	30
Start date	1 January 2018
Primary completion	1 January 2019
Estimated completion	1 January 2020
Sites	1 location across Egypt

Drugs / interventions tested

clomiphene citrate — full drug profile →
Saline cervical flushing — full drug profile →
Intrauterine Autologous platelet-rich plasma — full drug profile →

Conditions studied

Infertility, Female, Associated With Anovulation — all drugs for Infertility, Female, Associated With Anovulation →

Sponsor

Benha University

Who can join

Adults 18 to 35, female only, with Infertility, Female, Associated With Anovulation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective self-controlled clinical study. Women with clomiphene Citrate failure with thin endometrium less than 7 millimeters for at least 3 cycles will be selected (N = 30). Patients will receive 2 ovarian stimulation cycles with Clomiphene citrate (CC) 100 mg/ day for 5 days from cycle day 3. A control cycle (CC only cycle) woman will continue on CC alone plus cervical irrigation of cervix with 1 ml of 0.9% normal saline at cycle day 8 and 10 to assure patient-blinded method. The study group, the same will be done plus the intrauterine infusion of Autologous platelet-rich plasma (PRP) in 8th and 10th days of the cycle. In both groups, the endometrial thickness and Power Doppler evaluation of their endometrial and sub-endometrial blood flow will be measured on the day of Human Chorionic Gonadotropin (HCG) administration.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Therapeutic roles of platelet-rich plasma to restore female reproductive and endocrine dysfunction.
Wang X, Li J, Lu W, Gao F, et al · · 2024 · cited 8× · PMID 38654928 · DOI 10.3389/fendo.2024.1374382

Verify or expand the search:

Other trials of clomiphene citrate

Trials testing the same drug.

NCT04302532 — Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS · Phase 4 · completed

Other Benha University trials

Trials by the same sponsor.

NCT07526675 — Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer · NA · not yet recruiting
NCT07480031 — Determination of the Optimal Inspiratory Pressure to Decrease Incidence of Gastric Insufflation With Adequate Ventilatio · NA · not yet recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
NCT07300787 — miRNA in Pediatric Gastritis · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03770026 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Benha University
Last refreshed: 29 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03770026.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing