Last reviewed · How we verify
NCT03757767
The Fasting Study - Unraveling the Mechanistic Effects of Prolonged Fasting in Humans.
NA trial testing Fasting for 26-hours in Fasting in 24 participants. Completed in 22 January 2019.
22 January 2019
Quick facts
| Lead sponsor | Wageningen University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 12 November 2018 |
| Primary completion | 22 January 2019 |
| Estimated completion | 22 January 2019 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Fasting for 26-hours
Conditions studied
- Fasting — all drugs for Fasting →
- Adipose Tissue — all drugs for Adipose Tissue →
- Clinical Trial — all drugs for Clinical Trial →
- Lipid Metabolism — all drugs for Lipid Metabolism →
Sponsor
Wageningen University
Who can join
Adults 40 to 70, any sex, with Fasting or Adipose Tissue. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Elevated levels of plasma triglycerides are increasingly recognized as an important causal risk factor for cardiovascular disease and associated pathologies. Lowering plasma triglycerides may therefore be a therapeutic target to lower cardiovascular disease risk. With this study the investigators want to examine the effects of fasting on adipose tissue metabolism in humans.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue.
Ruppert PMM, Michielsen CCJR, Hazebroek EJ, Pirayesh A, et al · · 2020 · cited 53× · PMID 32504883 · DOI 10.1016/j.molmet.2020.101033
Verify or expand the search:
- PubMed search for NCT03757767
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Fasting
Currently open trials in the same condition.
- NCT07216989 — Fastomics: Metabolic and Therapeutic Effects of Prolonged Fasting · recruiting
- NCT06737224 — The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Metabolism and Glycemic Control in Healthy Active A · NA · recruiting
- NCT06779201 — Fasting Effects on Metabolism and Immunity Study in Human · NA · recruiting
- NCT06420739 — The Semaglutide Study · active not recruiting
- NCT06878781 — Postprandial Metabolome and Metabolic Flexibility · NA · recruiting
Other Wageningen University trials
Trials by the same sponsor.
- NCT07361406 — SweetSpot - The Effect of Non-nutritive Sweeteners on Health · NA · recruiting
- NCT07421466 — Umami Taste Intensity and Meal Intake · NA · completed
- NCT07075991 — Uptake and Excretion of a Single Dose of Oral 14C-labelled Polystyrene Microplastics in Healthy Volunteers · NA · completed
- NCT07059117 — Umami Taste Intensity and ad Libitum Meal Intake · NA · completed
- NCT06750497 — Forearm Immobilization in T2D · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03757767 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wageningen University
- Last refreshed: 24 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03757767.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing