Last reviewed · How we verify
NCT07075991
Uptake and Excretion of a Single Dose of Oral 14C-labelled Polystyrene Microplastics in Healthy Volunteers
NA trial testing 1 μm [14C]-labelled Polystyrene Microplastic in Kinetics in 6 participants. Completed in 31 August 2025.
31 August 2025
Quick facts
| Lead sponsor | Wageningen University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 6 |
| Start date | 19 June 2025 |
| Primary completion | 31 August 2025 |
| Estimated completion | 31 August 2025 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- 1 μm [14C]-labelled Polystyrene Microplastic — full drug profile →
Conditions studied
- Kinetics — all drugs for Kinetics →
Sponsor
Wageningen University
Who can join
Adults 18 to 65, any sex, with Kinetics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to understand how a small, labeled dose of microplastics moves through the human body (i.e., how it is absorbed, distributed, and excreted) in healthy adult volunteers aged 18-65 years (3 males, 3 females). The main questions it aims to answer are: * How much of the ingested microplastic is absorbed into the bloodstream? * How is the microplastic distributed and eliminated from the body through urine and feces? Participants will: * Take a single oral micro dose of 100 µg of 1 μm \[14C\]-labelled polystyrene microplastics (PS-MP). * Spend 24 hours in a clinical research facility for close monitoring and initial sample collection. * Provide blood, urine, and stool samples over a 5-day period (with daily short lab visits after the first day). This study does not include a comparison group.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07075991
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Kinetics
Currently open trials in the same condition.
- NCT06614166 — Food Trial to Evaluate the Kinetics of the Medical Foods SBD111 and SBD121 Persistence in Healthy Adults · NA · active not recruiting
- NCT04056078 — Nordic Throwing Shoulder Project (NTS - Project) · recruiting
Other Wageningen University trials
Trials by the same sponsor.
- NCT07361406 — SweetSpot - The Effect of Non-nutritive Sweeteners on Health · NA · recruiting
- NCT07421466 — Umami Taste Intensity and Meal Intake · NA · completed
- NCT07059117 — Umami Taste Intensity and ad Libitum Meal Intake · NA · completed
- NCT06750497 — Forearm Immobilization in T2D · NA · recruiting
- NCT05920148 — The Immu-KNEE-ty Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07075991 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wageningen University
- Last refreshed: 20 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07075991.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing