NCT03753867 is a Phase 1 clinical trial of Acitretin in HIV Infections, sponsored by Ottawa Hospital Research Institute.

Who is sponsoring NCT03753867?

NCT03753867 is sponsored by Ottawa Hospital Research Institute.

What drugs are being tested in NCT03753867?

Interventions in NCT03753867: Acitretin.

What condition does NCT03753867 study?

NCT03753867 studies HIV Infections.

Is NCT03753867 still recruiting?

NCT03753867 is currently withdrawn. Last updated 4 March 2020.

Last reviewed 2020-03-04 · How we verify

NCT03753867

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RA Effect on Cell Surface Molecules in Vivo

Withdrawn Phase 1 Last updated 4 March 2020

What this trial tests

Phase 1 trial testing Acitretin in HIV Infections. Withdrawn.

Timeline

7 January 2019

Primary endpoint
8 May 2019

8 May 2019

Quick facts

Lead sponsor	Ottawa Hospital Research Institute
Phase	Phase 1
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Start date	7 January 2019
Primary completion	8 May 2019
Estimated completion	8 May 2019

Drugs / interventions tested

Acitretin (ACITRETIN) — full drug profile →

Conditions studied

HIV Infections — all drugs for HIV Infections →

Sponsor

Ottawa Hospital Research Institute

Who can join

Adults 18 to 65, male only, with HIV Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will follow a group of healthy male participants for about 18 weeks to see the effect of taking Acitretin on their immune cells

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Fighting HIV-1 Persistence: At the Crossroads of "Shoc-K and B-Lock".
Acchioni C, Palermo E, Sandini S, Acchioni M, et al · · 2021 · cited 14× · PMID 34832672 · DOI 10.3390/pathogens10111517
Pattern Recognition Receptor Ligands as an Emerging Therapeutic Agent for Latent HIV-1 Infection.
Takahama S, Yamamoto T. · · 2020 · cited 9× · PMID 32457851 · DOI 10.3389/fcimb.2020.00216

Verify or expand the search:

Other trials of Acitretin

Trials testing the same drug.

NCT06739551 — Systemic Treatment Options for Generalized Lichen Planus · Phase 2 · not yet recruiting
NCT04537689 — Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis · Phase 4 · recruiting
NCT04245319 — Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation · NA · unknown
NCT05203354 — Omentin-1 Level in Psoriatic Patients Treated With Narrowband Ultraviolet B Phototherapy Versus Acitretin · Phase 4 · completed

Other recruiting trials for HIV Infections

Currently open trials in the same condition.

NCT07225530 — Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR) · NA · recruiting
NCT07202546 — A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · recruiting
NCT06694753 — Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall · Phase 1 · recruiting
NCT07235852 — Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention · NA · recruiting
NCT06665646 — Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Ad · Phase 1 · recruiting

Other Ottawa Hospital Research Institute trials

Trials by the same sponsor.

NCT07464080 — Advanced Brain Imaging-TKA (fMRI-TKA) · NA · recruiting
NCT07171567 — Vacuum Therapy for the Treatment of Penile Numbness/Sensory Changes · EARLY_PHASE1 · recruiting
NCT07058025 — Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants · Phase 2 · not yet recruiting
NCT07177833 — Title Fractioned CO2 Laser in the Treatment of Chronic Phase Peyronie's Disease · Phase 1 · recruiting
NCT06929767 — Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need Antibiotic · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03753867 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ottawa Hospital Research Institute
Last refreshed: 4 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03753867.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing