Who is sponsoring NCT03744156?

NCT03744156 is sponsored by University of Missouri-Columbia.

What drugs are being tested in NCT03744156?

Interventions in NCT03744156: Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education.

What condition does NCT03744156 study?

NCT03744156 studies Fibromyalgia, Insomnia, Chronic Widespread Pain.

Is NCT03744156 still recruiting?

NCT03744156 is currently completed. Last updated 1 October 2025.

Last reviewed 2025-10-01 · How we verify

NCT03744156: SPIN-II

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sleep and Pain Interventions in Women With Fibromyalgia

Completed NA Last updated 1 October 2025

What this trial tests

NA trial testing Cognitive Behavioral Treatment-Insomnia in Fibromyalgia in 131 participants. Completed in 31 May 2025.

Timeline

7 February 2019

Primary endpoint
31 May 2025

31 May 2025

Quick facts

Lead sponsor	University of Missouri-Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	131
Start date	7 February 2019
Primary completion	31 May 2025
Estimated completion	31 May 2025
Sites	1 location across United States

Drugs / interventions tested

Cognitive Behavioral Treatment-Insomnia
Sleep Hygiene Education

Conditions studied

Fibromyalgia — all drugs for Fibromyalgia →
Insomnia — all drugs for Insomnia →
Chronic Widespread Pain — all drugs for Chronic Widespread Pain →

Sponsor

University of Missouri-Columbia

Who can join

18 and older, female only, with Fibromyalgia or Insomnia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Neural activation changes in response to pain following cognitive behavioral therapy for patients with comorbid fibromyalgia and insomnia: a pilot study.
McCrae CS, Craggs JG, Curtis AF, Nair N, et al · · 2022 · cited 10× · PMID 34310276 · DOI 10.5664/jcsm.9540
Protocol for the impact of CBT for insomnia on pain symptoms and central sensitisation in fibromyalgia: a randomised controlled trial.
McCrae CS, Curtis AF, Craggs J, Deroche C, et al · · 2020 · cited 6× · PMID 32933953 · DOI 10.1136/bmjopen-2019-033760
Preliminary investigation of the interactive role of physiological arousal and insomnia complaints in gray matter volume alterations in chronic widespread pain.
Curtis AF, Nair N, Hayse B, McGovney K, et al · · 2024 · cited 2× · PMID 37823586 · DOI 10.5664/jcsm.10860

Verify or expand the search:

Other recruiting trials for Fibromyalgia

Currently open trials in the same condition.

NCT02285868 — ATI Evidence-based Guide Investigating Clinical Services · active not recruiting
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NCT05901259 — The EXOPULSE Study - a Database for Routine Follow-up of Clinical Outcomes · recruiting
NCT07358754 — The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor · recruiting
NCT07465991 — The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia · NA · recruiting

Other University of Missouri-Columbia trials

Trials by the same sponsor.

NCT07478172 — Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease · NA · recruiting
NCT07385105 — Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI) · NA · not yet recruiting
NCT07067502 — Impact of Biphasic Cuirass Ventilation Compared to Non Invasive Ventilation in High Risk Extubations · NA · not yet recruiting
NCT07424079 — Metacognitive Strategy Training Intervention for Transition-Age Youth With Cerebral Palsy · NA · not yet recruiting
NCT07216196 — The Feasibility of a Remote Problem-Solving Intervention for Autistic Adolescents or Young Adults and a Caregiver · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03744156 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Missouri-Columbia
Last refreshed: 1 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03744156.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing