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NCT03740815
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
NA trial testing Serratus plane block in Anesthesia in 15 participants. Completed in 2 March 2021.
2 March 2021
Quick facts
| Lead sponsor | Instituto Nacional de Cancer, Brazil |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 15 |
| Start date | 25 September 2018 |
| Primary completion | 2 March 2021 |
| Estimated completion | 2 March 2021 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Serratus plane block
- Axillary dissection
- Intravenous sedation — full drug profile →
Conditions studied
- Anesthesia — all drugs for Anesthesia →
- Regional Anesthesia Morbidity — all drugs for Regional Anesthesia Morbidity →
- Axillary Metastases — all drugs for Axillary Metastases →
- Nerve Block — all drugs for Nerve Block →
Sponsor
Instituto Nacional de Cancer, Brazil — full company profile →
Who can join
18 and older, any sex, with Anesthesia or Regional Anesthesia Morbidity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
INTRODUCTION: The axillary lymphadenectomy procedure is known to be associated with late postoperative complications, such as chronic pain and changes in shoulder mobility. Recently, several thoracic ultrasound guided interfascial blocks have been described, including serratus plane block. These blocks were associated with reduced postoperative pain scores in breast surgeries but were never evaluated in axillary dissection. The safety and feasibility of performing axillary dissection under local anesthesia and tumescent anesthesia associated with sedation has been demonstrated in case series, although it is not already the standard technique. DISCUSSION: This project aims to investigate the feasibility of the serratus plane block associated with intra-venous sedation in a prospective case series including 15 patients submitted to axillary dissection, by scoring patient and surgeon satisfaction with the technique, pain, quality of life with EORTC QLQ-C30 questionnaire, and quality of recovery with QoR-40 questionnaire in the first 30 postoperative days.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Serratus plane block with sedation for patients submitted to axillary dissection: a prospective case series.
Theobald D, Araujo BLC, Thuler LCS, Fiorelli RKA. · · 2023 · PMID 36790226 · DOI 10.1590/0100-6991e-20233398-en
Verify or expand the search:
- PubMed search for NCT03740815
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03740815 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto Nacional de Cancer, Brazil
- Last refreshed: 8 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03740815.
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