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NCT06217224: PBMT/MTX
Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
NA trial testing Preventive photobiomodulation Therapy (PBMT) in Mucositis Oral in 53 participants. Status unknown.
30 June 2025
Quick facts
| Lead sponsor | Instituto Nacional de Cancer, Brazil |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 53 |
| Start date | 17 October 2022 |
| Primary completion | 30 June 2025 |
| Estimated completion | 30 July 2025 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Preventive photobiomodulation Therapy (PBMT)
Conditions studied
- Mucositis Oral — all drugs for Mucositis Oral →
Sponsor
Instituto Nacional de Cancer, Brazil — full company profile →
Who can join
Under 19, any sex, with Mucositis Oral. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate the photobiomodulation therapy (PBMT) for the prevention of oral mucositis in osteosarcoma patients submitted to high doses of methotrexate, through two different protocols. As a hypothesis, photobiomodulation for the prevention of oral mucositis after cycles of Cisplatin, Doxorubicin and Methotrexate is more effective than just the application of preventive low-power laser after Methotrexate alone.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06217224
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other Instituto Nacional de Cancer, Brazil trials
Trials by the same sponsor.
- NCT06708702 — Copaíba-based Mouthwash in Oral Mucotitis Prevention and Treatment in Oral Cancer Patients During Radioteraphy · Phase 2 · withdrawn
- NCT06299462 — PTCy and ATG for MSD and MUD Transplants · Phase 1, PHASE2 · recruiting
- NCT06071637 — Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT · Phase 3 · recruiting
- NCT05535452 — Photobiomodulation for Prevention of Radiodermatitis in Women With Breast Cancer Undergoing Adjuvant Radiotherapy · NA · unknown
- NCT04861220 — Surgical Pre-habilitation in Breast Cancer. · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06217224 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto Nacional de Cancer, Brazil
- Last refreshed: 22 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06217224.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing