NCT03734900 is a Phase 4 clinical trial of Saline injection in Osteoarthritis (OA) of the Knee, sponsored by National Taiwan University Hospital.

Who is sponsoring NCT03734900?

NCT03734900 is sponsored by National Taiwan University Hospital.

What drugs are being tested in NCT03734900?

Interventions in NCT03734900: Saline injection, PRP injection, PL injection.

What condition does NCT03734900 study?

NCT03734900 studies Osteoarthritis (OA) of the Knee.

Is NCT03734900 still recruiting?

NCT03734900 is currently status unknown. Last updated 20 September 2021.

Last reviewed 2021-09-20 · How we verify

NCT03734900

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial

Status unknown Phase 4 Last updated 20 September 2021

What this trial tests

Phase 4 trial testing Saline injection in Osteoarthritis (OA) of the Knee in 150 participants. Status unknown.

Timeline

15 May 2018

Primary endpoint
14 May 2022

14 May 2022

Quick facts

Lead sponsor	National Taiwan University Hospital
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	150
Start date	15 May 2018
Primary completion	14 May 2022
Estimated completion	14 May 2022
Sites	1 location across Taiwan

Drugs / interventions tested

Saline injection
PRP injection
PL injection

Conditions studied

Osteoarthritis (OA) of the Knee — all drugs for Osteoarthritis (OA) of the Knee →

Sponsor

National Taiwan University Hospital

Who can join

Adults 50 to 80, any sex, with Osteoarthritis (OA) of the Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will focus on grade I to III knee osteoarthritis by randomized controlled trials which comparing the effectiveness between placebo, autologous platelet rich plasma and autologous platelet lysate injections.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence.
Gupta A, Maffulli N. · · 2024 · cited 10× · PMID 39340713 · DOI 10.1007/s40122-024-00661-y

Verify or expand the search:

Other trials of Saline injection

Trials testing the same drug.

NCT07086677 — A Study to Learn About How a New Pneumococcal Vaccine Works in Adults · Phase 1 · active not recruiting
NCT06634823 — Efficacy of Intramuscular Steroid Injection for Chronic Cough. · EARLY_PHASE1 · recruiting
NCT06774807 — Blocking of the Gut Hormone Receptor for Glucagon-like Peptide 2 (GLP-2) by the GLP-2 Receptor Antagonist GLP-2(3-33) · NA · completed
NCT07352241 — Repeated Injections of i-PRF for Decreasing Root Resorption After the Orthodontic Treatment. · NA · completed
NCT06048874 — FNB in ACL Recon Under SA · NA · not yet recruiting

Other recruiting trials for Osteoarthritis (OA) of the Knee

Currently open trials in the same condition.

NCT07231471 — Platelet Rich Plasma for Musculoskeletal Conditions · NA · recruiting
NCT06929871 — Mako Cementless TKA vs Mako Cemented TKA · NA · recruiting
NCT06865079 — 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femo · Phase 2 · active not recruiting
NCT06702046 — The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis · NA · recruiting
NCT06805188 — Clinical Study of Acupuncture Treatment of Knee Osteoarthritis · NA · recruiting

Other National Taiwan University Hospital trials

Trials by the same sponsor.

NCT06936917 — Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest · not yet recruiting
NCT05396222 — A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar · NA · not yet recruiting
NCT07532356 — Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk · not yet recruiting
NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
NCT07382024 — Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03734900 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 20 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03734900.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing