NCT03734250 is a clinical trial in Vitamin D Deficiency, sponsored by Duzce University.

Who is sponsoring NCT03734250?

NCT03734250 is sponsored by Duzce University.

What condition does NCT03734250 study?

NCT03734250 studies Vitamin D Deficiency, Neuromuscular Block, Neuromuscular Block Problem.

Is NCT03734250 still recruiting?

NCT03734250 is currently completed. Last updated 7 November 2018.

Last reviewed 2018-11-07 · How we verify

NCT03734250

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

D Vitamin Effects on Neuromuscular Blocker Reverse Time

Completed Last updated 7 November 2018

What this trial tests

trial in Vitamin D Deficiency in 84 participants. Completed in 1 March 2018.

Timeline

1 November 2014

Primary endpoint
1 March 2018

1 March 2018

Quick facts

Lead sponsor	Duzce University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	84
Start date	1 November 2014
Primary completion	1 March 2018
Estimated completion	1 March 2018

Conditions studied

Vitamin D Deficiency — all drugs for Vitamin D Deficiency →
Neuromuscular Block — all drugs for Neuromuscular Block →
Neuromuscular Block Problem — all drugs for Neuromuscular Block Problem →

Sponsor

Duzce University

Who can join

Adults 18 to 65, any sex, with Vitamin D Deficiency or Neuromuscular Block. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background/aim: Investigators aimed to investigate the effect of D vitamin levels on Sugammadex and Neostigmine reverse durations in the study. Materials and methods: Eighty patients between 18 and 65 years, with ASA I-III status who were undergoing surgery under general anaesthesia were included the study. All patients were randomly divided into two groups with double blindness and 1.25 (OH) 2 vitamin D, 25 (OH) 2 vitamin D, and calcium levels were measured. At the end of the operation, 2 mg/kg of Sugammadex was administered to one group and Atropine + Neostigmine to the other group. The patients were also divided into two groups as to whether their vitamin D levels were ≥ 30 ng/mL or below. A train of four values was recorded after a hypnotic agent was given at the beginning and throughout the operation. The time to complete the disappearance of response to TOF stimulation was recorded as T0. End of the operation: When 2 responses to TOF stimulation were taken, the following times were recorded until the extubation phase by administering at least 2 mg/kg of Sugammadex or 0.05 mg/kg of Neostigmine 0.05 mg/kg of Atropine per kg of body weight. The time until the TOF value reached 50,70,90% and extubation were recorded.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The effect of vitamin D status on different neuromuscular blocker agents reverse time
Yorulmaz IS, Demiraran Y, Özlü O, Dost B. · · 2020 · cited 2× · PMID 32151115 · DOI 10.3906/sag-1901-115

Verify or expand the search:

Other recruiting trials for Vitamin D Deficiency

Currently open trials in the same condition.

NCT07317830 — Effects of Different Vitamin D3 Formulations in Vitamin D-Deficient Adults · NA · recruiting
NCT07366970 — Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D? · NA · recruiting
NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
NCT07200011 — Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures · active not recruiting

Other Duzce University trials

Trials by the same sponsor.

NCT07300176 — Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway · active not recruiting
NCT07163468 — Neuromusculoskeletal Alterations After ACL Injury · completed
NCT07468240 — Mindfulness-Based Psychoeducation for Burnout, Decision-Making, and Existential Anxiety in High-Risk Unit Nurses · NA · completed
NCT07152093 — Development of an Artificial Intelligence-Based Model for Predicting Difficult Intubation Using Video Laryngoscopic Imag · completed
NCT07057362 — Effect of Vitamin D Deficiency on the Frequency and Severity of Spinal Anesthesia-Induced Hypotension in Pregnant Women · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03734250 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duzce University
Last refreshed: 7 November 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03734250.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing