Last reviewed · How we verify
NCT03733041
Neuromodulation for Exercise Adherence
NA trial testing Repetitive Transcranial Magnetic Stimulator in Executive Dysfunction in 72 participants. Completed in 31 May 2025.
31 January 2025
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 1 April 2019 |
| Primary completion | 31 January 2025 |
| Estimated completion | 31 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Repetitive Transcranial Magnetic Stimulator
- Sham treatment — full drug profile →
- Nintendo Wii-Fit exercises
Conditions studied
- Executive Dysfunction — all drugs for Executive Dysfunction →
- Poor Exercise Adherence — all drugs for Poor Exercise Adherence →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
60 and older, any sex, with Executive Dysfunction or Poor Exercise Adherence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lack of adherence to an exercise program is a major problem for older Veterans. Several fall prevention programs fail in the home setting due to lack of adherence. Exercise adherence is dependent on brain function among other factors. Magnetic stimulation of the front part of the brain improves brain function necessary for planning and following-through. The investigators propose a three-phase study in 106 sedentary older Veterans. Everyone will be trained on use of the exergames, Nintendo Wii-Fit, that the investigators' team has found beneficial in improving balance and gait. They will be asked to exercise using Wii-Fit at home for 45 minutes daily five days/week for 12-weeks. Those that exercise less than recommended dose and those that exercise adequately but have low executive function will receive either real or sham magnetic stimulation to the front part of their brain over ten sessions paired with exercise training. All subjects will further complete 24-weeks of Wii-Fit home exercises. Adherence, executive function, balance and gait, self-efficacy, delay discounting, and falls will be measured periodically.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03733041
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Executive Dysfunction
Currently open trials in the same condition.
- NCT06608966 — Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy · NA · recruiting
- NCT06267430 — Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD · NA · recruiting
- NCT06447909 — Randomized Controlled Trial of a Behavioral Training App · NA · recruiting
- NCT05874791 — Executive Control Training for Adolescents With ADHD: A Randomized Controlled Effectiveness Trial · NA · active not recruiting
- NCT05726721 — Profiling the Dynamic of Binge Eating Disorder (PRODY-BED) · recruiting
Other VA Office of Research and Development trials
Trials by the same sponsor.
- NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
- NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
- NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
- NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
- NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03733041 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 2 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03733041.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing