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NCT03730402
Laparoscopic Assisted Plane Block (LAPB) Trial
Phase 4 trial testing Bupivacaine in Opioid Use in 34 participants. Terminated before completion.
14 April 2021
Quick facts
| Lead sponsor | Santa Barbara Cottage Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 34 |
| Start date | 4 February 2019 |
| Primary completion | 14 April 2021 |
| Estimated completion | 14 April 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Bupivacaine (BUPIVACAINE) — full drug profile →
- Exparel 266 milligram Per 20 ML Injection — full drug profile →
- Saline
Conditions studied
- Opioid Use — all drugs for Opioid Use →
Sponsor
Santa Barbara Cottage Hospital
Who can join
Adults 18 to 80, any sex, with Opioid Use. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03730402
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bupivacaine
Trials testing the same drug.
- NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
- NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
- NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT07146685 — Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study · Phase 4 · not yet recruiting
Other recruiting trials for Opioid Use
Currently open trials in the same condition.
- NCT07342504 — Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist · NA · recruiting
- NCT07004686 — Effect of MGRNOX-Guided General Anesthesia on Opioid Consumption in Patients · NA · recruiting
- NCT06981195 — Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects · Phase 2 · recruiting
- NCT06806163 — Machine-Learning Prediction and Reducing Overdoses With EHR Nudges · NA · recruiting
- NCT06909851 — Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block · NA · recruiting
Other Santa Barbara Cottage Hospital trials
Trials by the same sponsor.
- NCT04946162 — The Use of Tadalafil in Confirmed COVID-19 Pneumonia. · Phase 4 · withdrawn
- NCT03788889 — Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine · Phase 4 · withdrawn
- NCT03577379 — Vascular Changes of Rotator Cuff Repair Augmented With a Whole Blood Fibrin Clot · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03730402 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Santa Barbara Cottage Hospital
- Last refreshed: 1 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03730402.
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