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NCT03729700
The Effect of Almonds on Facial Aesthetics and Modulation of the Microbiome and Lipidome
NA trial testing Almond in Wrinkle in 60 participants. Completed in 22 June 2021.
1 June 2021
Quick facts
| Lead sponsor | University of California, Davis |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 60 |
| Start date | 22 October 2018 |
| Primary completion | 1 June 2021 |
| Estimated completion | 22 June 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Almond
Conditions studied
- Wrinkle — all drugs for Wrinkle →
Sponsor
University of California, Davis
Who can join
Adults 18 to 100, female only, with Wrinkle. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigator hypothesizes that regular consumption of almonds will 1) improve the facial wrinkle severity in post-menopausal women, 2) improve the evenness of facial skin pigmentation, 3) diversify the gut microbiome and increase the short chain fatty acids in the blood, and 4) improve the skin barrier biophysical properties.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation.
Rybak I, Carrington AE, Dhaliwal S, Hasan A, et al · · 2021 · cited 13× · PMID 33673587 · DOI 10.3390/nu13030785
Verify or expand the search:
- PubMed search for NCT03729700
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Almond
Trials testing the same drug.
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- NCT05322304 — Almonds and Cognitive Functions · NA · unknown
- NCT05176197 — Effects of Almonds on Glycemia in Adults With Elevated Hemoglobin A1c Concentrations · NA · unknown
- NCT05059639 — Exploring the Role of Almonds in Enhancing Immune Strength · NA · completed
- NCT04787718 — Almond for Physical Performance · NA · completed
Other recruiting trials for Wrinkle
Currently open trials in the same condition.
- NCT06868615 — AVAVA MIRIA General Use · NA · recruiting
- NCT06571721 — The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles · NA · recruiting
- NCT06385171 — Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation · recruiting
- NCT06557434 — AV-23-001 AVAVA MIRIA Pilot Study · NA · active not recruiting
- NCT06202274 — Clinical Study to Evaluate the Safety and Efficacy of Candela Technology · NA · active not recruiting
Other University of California, Davis trials
Trials by the same sponsor.
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- NCT07384767 — Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing · Phase 2 · not yet recruiting
- NCT07267494 — Image-Guided Herniorrhaphy Study · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03729700 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Davis
- Last refreshed: 7 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03729700.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing