NCT03726086 (PALSS) is a clinical trial of laryngoscopy in Intubation, Intratracheal, sponsored by Johns Hopkins University.

Who is sponsoring NCT03726086?

NCT03726086 is sponsored by Johns Hopkins University.

What drugs are being tested in NCT03726086?

Interventions in NCT03726086: laryngoscopy.

What condition does NCT03726086 study?

NCT03726086 studies Intubation, Intratracheal, Critical Illness, Mechanical Ventilation Complication, Complication of Ventilation Therapy.

Is NCT03726086 still recruiting?

NCT03726086 is currently completed. Last updated 6 July 2023.

Last reviewed 2023-07-06 · How we verify

NCT03726086: PALSS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Post-extubation Assessment of Laryngeal Symptoms and Severity

Completed Last updated 6 July 2023

What this trial tests

trial testing laryngoscopy in Intubation, Intratracheal in 365 participants. Completed in 10 June 2023.

Timeline

12 February 2019

Primary endpoint
10 June 2023

10 June 2023

Quick facts

Lead sponsor	Johns Hopkins University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	365
Start date	12 February 2019
Primary completion	10 June 2023
Estimated completion	10 June 2023
Sites	1 location across United States

Drugs / interventions tested

laryngoscopy

Conditions studied

Intubation, Intratracheal — all drugs for Intubation, Intratracheal →
Critical Illness — all drugs for Critical Illness →
Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
Complication of Ventilation Therapy — all drugs for Complication of Ventilation Therapy →

Sponsor

Johns Hopkins University

Who can join

18 and older, any sex, with Intubation, Intratracheal or Critical Illness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to learn more about voice and airway problems that patients experience during and after the time patients have an oral endotracheal tube in patients' airway to help patients breathe while receiving mechanical ventilation in an intensive care unit (ICU).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Feasibility of Endoscopic Evaluations of Laryngeal Function After Extubation for Research in Critically Ill Adults.
Pandian V, Cherukuri SPS, Koneru M, Reddy GSKJ, et al · · 2025 · PMID 40153258 · DOI 10.1044/2025_ajslp-23-00464
Post-extubation Assessment of Laryngeal Symptoms and Severity (PALSS) in the Intensive Care Unit: Protocol of a Prospective Cohort Study.
Pandian V, Cherukuri SPS, Koneru M, Karne V, et al · · 2024 · PMID 38264200

Verify or expand the search:

Other trials of laryngoscopy

Trials testing the same drug.

NCT05902013 — Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation · NA · recruiting

Other recruiting trials for Intubation, Intratracheal

Currently open trials in the same condition.

NCT07351227 — Pediatric Airway: Noninferiority Trial of Devices for Intubation Assessment · NA · recruiting
NCT06953414 — Classification and Prediction of Difficult Awake Tracheal Intubation With Flexible Bronchoscopes · recruiting
NCT07185074 — Intubation Conditions During ERCP With Lidocaine Aerosol Plus Low-dose Cisatracurium or Conventional-dose Cisatracurium · Phase 4 · active not recruiting

Other Johns Hopkins University trials

Trials by the same sponsor.

NCT06236542 — Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety · NA · not yet recruiting
NCT07532252 — Daridorexant for Alcohol Use Disorder · Phase 2 · not yet recruiting
NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
NCT07079111 — 3D Printed Occlusal Splints for Intraoperative Use · NA · not yet recruiting
NCT02998502 — The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03726086 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
Last refreshed: 6 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03726086.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing