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NCT03719053
Single Dose Truvada Study
Phase 1 trial testing Tenofovir in Medication Adherence in 44 participants. Completed in 30 June 2020.
30 June 2020
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 44 |
| Start date | 25 October 2018 |
| Primary completion | 30 June 2020 |
| Estimated completion | 30 June 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Tenofovir — full drug profile →
Conditions studied
- Medication Adherence — all drugs for Medication Adherence →
- HIV Prevention — all drugs for HIV Prevention →
Sponsor
Johns Hopkins University
Who can join
18 and older, any sex, with Medication Adherence or HIV Prevention. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study examines tenofovir (TFV) drug concentrations in adults one day after taking a single dose of Truvada® - a pill used to prevent and treat HIV infection. The results of this study will be used to improve the (efficacy/accuracy) of a white coat adherence (WCA) detection test - a blood test that can be used to indicate medication adherence. Participants will receive one dose of Truvada®, and provide 2 total samples of blood.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03719053
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tenofovir
Trials testing the same drug.
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- NCT02650271 — Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC · Phase 3 · completed
- NCT04539119 — Entecavir and Tenofovir Versus Entecavir in Lymphoma Patients With Positive HBV DNA · Phase 3 · unknown
- NCT04431375 — Efficacy of Addition of Fecal Microbiota Transplant (FMT) and Plasma Exchange to Tenofovir in Comparison to Monotherapy · NA · unknown
- NCT03986970 — The CHAPS Trial: Combined HIV Adolescent PrEP and Prevention · Phase 2 · completed
Other recruiting trials for Medication Adherence
Currently open trials in the same condition.
- NCT07420634 — Multilevel Ecological and COM-B Determinants of Medication Adherence in Adults With Diabetes · recruiting
- NCT06876233 — Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication · NA · recruiting
- NCT05624931 — Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa · NA · recruiting
- NCT06949774 — INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND) · NA · recruiting
- NCT06569290 — Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Sci · NA · active not recruiting
Other Johns Hopkins University trials
Trials by the same sponsor.
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- NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03719053 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 16 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03719053.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing