NCT03717376: SCHEMAF

Movement Disorders and Early Maladaptive Schemas

Completed Last updated 31 January 2022

What this trial tests

trial testing Self-questionnaire YSQ-S3 (Young Schema Questionnaire) in Functional Movement Disorder in 80 participants. Completed in 12 February 2020.

Timeline

12 February 2019

Primary endpoint
12 February 2019

12 February 2020

Quick facts

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Status	Completed
Study type	OBSERVATIONAL
Enrollment	80
Start date	12 February 2019
Primary completion	12 February 2019
Estimated completion	12 February 2020
Sites	1 location across France

Drugs / interventions tested

• Self-questionnaire YSQ-S3 (Young Schema Questionnaire)

Conditions studied

• Functional Movement Disorder — all drugs for Functional Movement Disorder →
• Parkinson Disease — all drugs for Parkinson Disease →
• Dystonic Disorders — all drugs for Dystonic Disorders →

Sponsor

Assistance Publique - Hôpitaux de Paris — full company profile →

Who can join

18 and older, any sex, with Functional Movement Disorder or Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Functional neurological disorders (FND) are neurological symptoms that cannot be explained by a lesion or related to an identified dysfunction of the central nervous system. FND are under-diagnosed, although common and highly disabling. Childhood trauma events are found in 30% to 80% of FND patients, and are more common in people with functional neurological disorder than in healthy controls and patient controls. Overall, risks factors, perpetuating factors and maintaining factors have been described in FND, although none of the studies have analysed the prevalence of Early Maladaptive Schemas (EMS) in these patients. EMS, as measured with the Young Schema Questionnaire (YSQ), are proposed to underlie a variety of mental health problems, in particular Personality Disorders. We hypothesize that some of these early maladaptive schemas may participate in the psychopathology and severity of FND.

The main outcome of this study is to assess the prevalence of early maladaptive schemas in patients presenting with Functional Movement Disorders in comparison to patients presenting with Parkinson's Disease or Organic Dystonia. The secondary outcomes are to further analyse the underlying relation of these early maladaptive schemas and (i) the severity of the motor symptoms, (ii) anxiety and/or depression, (iii) the occurrence of childhood trauma events in our participants.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.